Results 231 to 240 of about 597,026 (313)

Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models

Advanced Science, EarlyView.
Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler, Tim Lange, Sophia‐Marie Bach, Soeren S. Lienkamp, Nicole Endlich   +4 more
wiley   +1 more source

Climate warming drives population trajectories of freshwater fish. [PDF]

Proc Natl Acad Sci U S A
Brown TM, O'Connor J, Genner MJ.
europepmc   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source

Global lake phytoplankton proliferation intensifies climate warming. [PDF]

Nat Commun
Shi W, Qin B, Zhang Q, Paerl HW, Van Dam B, Jeppesen E, Zeng C.   +6 more
europepmc   +1 more source

Climate warming

, 2011
openaire   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Microbiome Adaptation Could Amplify Modeled Projections of Global Soil Carbon Loss With Climate Warming. [PDF]

Glob Chang Biol
Abs E, Saleska SR, Allison SD, Ciais P, Song Y, Weintraub MN, Ferriere R.   +6 more
europepmc   +1 more source

Highly Robust Membrane Electrode Assembly Using Engineered Dual‐Phase Iridium Oxide Catalysts Breaking the Activity–Durability Trade‐Off in Proton Exchange Membrane Water Electrolysis

Advanced Science, EarlyView.
The dual‐phase iridium oxide catalyst was synthesized via a hard‐template‐assisted method, overcoming the conventional activity–durability trade‐off observed in Ir‐based catalysts. The HDP‐IrOx exhibits excellent catalytic activity and long‐term stability through the synergistic coupling between amorphous and crystalline phases, offering new insights ...
Ho Seong Yang, Song Gyun Kim, Rubin Shin, Youngin Cho, Chanho Pak   +4 more
wiley   +1 more source

Climate warming detected in caves of the European Alps. [PDF]

Sci Rep
Obleitner F, Trüssel M, Spötl C.
europepmc   +1 more source

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source