Results 151 to 160 of about 612,341 (304)

Variations of Urban Thermal Risk with Local Climate Zones. [PDF]

Int J Environ Res Public Health, 2023
Xin J, Yang J, Jiang Y, Shi Z, Jin C, Xiao X, Xia JC, Yang R.   +7 more
europepmc   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

The spatial configuration of local climate zones reveals effects on wayfinding in human walking. [PDF]

PLoS One, 2023
Fan PY, Chun KP, Tan ML, Mah DN, Mijic A, Strickert G, Yetemen O.   +6 more
europepmc   +1 more source

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

Forest loss intensifies meteorological drought in more than half of Earth's climate zones. [PDF]

Sci Adv
Li X, Wu T, Xia K, Tang H, Wang X, Wang S, Lyne V, Zu Y.   +7 more
europepmc   +1 more source

Transient Thermal Analysis of Concrete Box Girders: Assessing Temperature Variations in Canadian Climate Zones. [PDF]

Sensors (Basel), 2023
Nassar M, Amleh L.
europepmc   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

LSTM-Based Recurrent Neural Network Predicts Influenza-Like-Illness in Variable Climate Zones. [PDF]

Immun Inflamm Dis
Amendolara A, Gowans C, Barton J, Payne A, Sant D.   +4 more
europepmc   +1 more source

Measuring the relationships between various urban green spaces and local climate zones. [PDF]

Sci Rep, 2023
Kirschner V, Macků K, Moravec D, Maňas J.   +3 more
europepmc   +1 more source

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source