Results 41 to 50 of about 249,105 (300)

Vulnerability of the agricultural sector to climate change: The development of a pantropical Climate Risk Vulnerability Assessment to inform sub-national decision making [PDF]

, 2019
As climate change continues to exert increasing pressure upon the livelihoods and agricultural sector of many developing and developed nations, a need exists to understand and prioritise at the sub national scale which areas and communities are most ...
Bourgoin, Clément, Läderach, Peter, Martinez-Valle, Armando, Parker, Louis   +3 more
core   +2 more sources

Microclimate Zoning Based on Double Clustering Method for Humid Climates with Altitudinal Gradient Variations: A Case Study of Colombia

Atmosphere
Climatic classification is essential for evaluating climate parameters that allow sustainable urban planning and resource management in countries with difficult access to meteorological information.
Cristian Mejía-Parada, Viviana Mora-Ruiz, Jonathan Soto-Paz, Brayan A. Parra-Orobio, Shady Attia   +4 more
doaj   +1 more source

Evaluation of modelling approaches for predicting the spatial distribution of soil organic carbon stocks at the national scale [PDF]

, 2014
Soil organic carbon (SOC) plays a major role in the global carbon budget. It can act as a source or a sink of atmospheric carbon, thereby possibly influencing the course of climate change.
Arrouays, D., Boulonne, L., Jolivet, C., Lacarce, E., Martin, M. P., Meersmans, J., Orton, T. G., Paroissien, J. B., Saby, N. P. A.   +8 more
core   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

COST 733 - WG4: Applications of weather type classification [PDF]

, 2008
The main objective of the COST Action 733 is to achieve a general numerical method for assessing, comparing and classifying typical weather situations in the European regions.
Bardossy, A., Bertalanic, R., Bogucka, M., Cahyanova, M., Caian, M., Casado, M.J., Demuzere, M., Fleig, A., Frei, C., Georgescu, F., Godlowska, J., Kassomenos, P., Latinov, L., Pastor, M.A., Pianko-Kluczynska, K., Pongracz, R., Prudhomme, C., Schiemann, R., Sepp, M., Stefan, S., Tallaksen, L, Tomaszewska, A.M., Ustrnul, Z.   +22 more
core  

Interface between pest risk science and policy : the EPPO perspective [PDF]

, 2013
The European and Mediterranean Plant Protection Organisation (EPPO) is an intergovernmental organization responsible for cooperation in plant protection in the European and Mediterranean region.
Baker, Richard, Brunel, Sarah, Petter, Françoise, Suffert, Muriel   +3 more
core   +2 more sources

Evaluating the ecological realism of plant species distribution models with ecological indicator values [PDF]

, 2020
Species distribution models (SDMs) are routinely applied to assess current as well as future species distributions, for example to assess impacts of future environmental change on biodiversity or to underpin conservation planning.
Ellenberg H., Ellenberg H., Fagerli H., Fourcade Y., Frank D., Hazeu G. W., Hennekens S. M., Hill M. O., Janssen J. A. M., Landolt E., Pignatti S., Schaminée J. H. J., Schaminée J. H. J., Schaminée J. H. J., Schaminée J. H. J., Settele J., Thuiller W.   +16 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Climatic Zoning using Multi-Variable Statistical Methods at East Azarbyjan Province [PDF]

محیط زیست و مهندسی آب, 2017
Climate is one of the most important and effective phenomenon of human life. Today's human, in order to develop industrial and municipal centers, and to increase food resources, needs to increase its information in the context of different climatic zones.
Hossein Rezaie, Zahra Rabiee, Zabihollah Khani Temeliyeh, Sakineh Khani Temeliyeh   +3 more
doaj