Results 171 to 180 of about 136,365 (269)

Enhancing Biogenic Formic Acid Production in the Modified OxFA Process by Acetonitrile Addition

Advanced Science, EarlyView.
In this study, the beneficial effect of using acetonitrile as a co‐solvent in the modified OxFA process is shown, outperforming methanol, demonstrating improved reaction kinetics combined with high selectivity for the HPA‐2 (H5PV2Mo10O40) catalyzed oxidation of xylose to FA.
Jan‐Dominik H. Krueger, Pegah Saedi, Maximilian J. Poller, Alberto Collauto, Jason P. Hallett, David Robinson, Maxie M. Roessler, Jakob Albert   +7 more
wiley   +1 more source

Impact of Climatic Factors on the Temporal Trend of Malaria in India from 1961 to 2021. [PDF]

Trop Med Infect Dis
Mayilsamy M, Veeramanoharan R, Jain K, Balakrishnan V, Rajaiah P.   +4 more
europepmc   +1 more source

Triple‐Negative Breast Cancer Cells Utilize IL8 and CXCL1 to Suppress NK Cells’ Function and Facilitate Cancer Metastasis

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan, Hongmei Yang, Renfei Wu, Meng Hao, Xiangpeng Chu, Chuxia Deng, Kathy Qian Luo   +6 more
wiley   +1 more source

Correction: The impact of climatic factors on tick-related hospital visits and borreliosis incidence rates in European Russia. [PDF]

PLoS One
Georgiades P, Ezhova E, Räty M, Orlov D, Kulmala M, Lelieveld J, Malkhazova S, Erguler K, Petäjä T.   +8 more
europepmc   +1 more source

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

Seasonal Variation in the Diversity of the Gut Microbiota of Short-Faced Moles Reveals the Associations of Climatic Factors on the Gut Microbiota of Subterranean Mammals. [PDF]

Ecol Evol
Xu D, Wu M, Gao Z, Zhao Y, Hu M, Wen Y, Wang L, Xu D, Chen L.   +8 more
europepmc   +1 more source

PANX2 Suppresses Lung Adenocarcinoma Progression by Inducing Disulfidptosis and Enhancing Antitumor Immunity

Advanced Science, EarlyView.
ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen, Zhao‐Yu Liu, Gao‐Wen Qu, Run‐Hao Zeng, Wen‐Xia Yao, Yong‐Bing Zhou, Xue Liang, Yu‐Xiong Lai   +7 more
wiley   +1 more source

Seasonality of medically attended norovirus gastroenteritis and its association with climatic factors within an US integrated healthcare system, 2016-2019. [PDF]

PLoS One
Mattison CP, Calderwood LE, Cates JE, Donald J, Hall AJ, Schmidt MA, Mirza SA.   +6 more
europepmc   +1 more source

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Plant Functional Traits Better Explain the Global Latitudinal Patterns of Leaf Insect Herbivory than Climatic Factors. [PDF]

Plants (Basel)
Ji Y, Yan X, Xu J, Jumak M, Zhang R, Wang L, Gao J.   +6 more
europepmc   +1 more source