Results 241 to 250 of about 657,952 (309)

MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Advanced Science, EarlyView.
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li   +10 more
wiley   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Impact of climatic factors on water quality parameters in tilapia broodfish ponds and predictive modeling of pond water temperature with ARIMAX. [PDF]

Heliyon
Siddique MAB, Mahalder B, Haque MM, Ahammad AKS.   +3 more
europepmc   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

Geo-climatic factors co-drive the phenotypic diversity of wild hemp (Cannabis sativa L.) in the Potohar Plateau and Lesser Himalayas. [PDF]

BMC Plant Biol
Younas M, Qureshi R, van Velzen R, Mashwani ZU, Saqib Z, Ali A, Rehman S, Farah MA, Al-Anazi KM.   +8 more
europepmc   +1 more source

Biodiversity and Spatiotemporal Variations of Mecoptera in Thailand: Influences of Elevation and Climatic Factors. [PDF]

Insects
Dokjan T, Bicha WJ, Suttiprapan P, Chuttong B, Chiu CI, Aupalee K, Saeung A, Saeung A, Sulin C, Srisuka W.   +9 more
europepmc   +1 more source

Relationship between climatic factors and the flea index of two plague hosts in Xilingol League, Inner Mongolia Autonomous Region. [PDF]

Biosaf Health
Zhang L, Wang Z, Chang N, Shang M, Wei X, Li K, Li J, Lun X, Ji H, Liu Q.   +9 more
europepmc   +1 more source

Observational study of ground-level ozone and climatic factors in Craiova, Romania, based on one-year high-resolution data. [PDF]

Sci Rep
Yildizhan H, Udriștioiu MT, Pekdogan T, Ameen A.   +3 more
europepmc   +1 more source

Effects of geographical, soil and climatic factors on the two marker secondary metabolites contents in the roots of Rubia cordifolia L. [PDF]

Front Plant Sci
Wang Y, Liu H, Yu S, Zhang Y, Huang Y, He X, Chen W.   +6 more
europepmc   +1 more source

Host genotype, soil composition, and geo-climatic factors shape the fonio seed microbiome. [PDF]

Microbiome
Tabassum N, Ahmed HI, Parween S, Sheikh AH, Saad MM, Krattinger SG, Hirt H.   +6 more
europepmc   +1 more source