Results 251 to 260 of about 391,518 (330)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Dietary factors and nutritional guidelines for sarcopenia in older adults: a narrative review. [PDF]

Korean J Community Nutr
Heo S, Yang SJ.
europepmc   +1 more source

A Proposal for the Preventive Method for the Wheel Climb Derailment

, 2008
Kazuhiko Nagase, Hironori HASHI
openalex   +2 more sources

Data driven fuel consumption prediction model for green aviation using radial basis function neural network. [PDF]

Sci Rep
Zhao Y, Wang Z, Wang X, Song Y, Han Y.
europepmc   +1 more source

The Development and Implementation of a Gamified Stair Climbing Intervention at an Individual Level

, 2014
Shayna M Fairbairn
openalex   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Advances in Gene Therapy for Inherited Haemoglobinopathies. [PDF]

Hematol Rep
Gaspar AB, Gaspar HB.
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Intuitive Polydimethylsiloxane Deposition Relying on Resource Conservative, Large Scale Compatible Capillary Flow Dynamics. [PDF]

ACS Omega
Kahwagi RF, Abdelmageed G, Sunny-Ekhalume E, Scott AJ, Hinds S, Koleilat GI.   +5 more
europepmc   +1 more source