Results 61 to 70 of about 391,518 (330)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
SvetoviThe article examines how social media, particularly YouTube, frame the representation of identity, place, and performance. Social media, with their reliance on algorithmic infrastructures, transform these representations into (hy-per)versions of the ...
Blaž Bajič
doaj +1 more source
Клиническая и экспериментальная тиреоидология, 2012 The purpose of the article is development, introduction into clinical practice and potency assignment of the protocol of preoperative thyroid and regional efflux of lymph examination and a new method of ultrasonic cervical glands assessment as well as ...
doaj +1 more source
Science, 2003 2 pages, 1 figure.-- PMID: 14684807 [PubMed]. Evolutionary biologists have long argued that adaptation to a particular environmental niche should constrain a population's ability to survive in other niches. In their Perspective, Elena and Sanjuán discuss new evolution experiments with populations of the bacterium Pseudomonas fluorescens (Buckling et al.
Elena, Santiago F., Sanjuán, Rafael
openaire +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
, 2008 Religion has been woven into the fabric of societies past and present, and the human desire to reach out to the divine is a very important component of society.
Szczebak, Joey
core +1 more source
, 2018 One of the ceremonies Shembe initiated was a barefoot three-day pilgrimage to the Holy Mountain, Nhlangakazi. Shembe said the Word had led him to this low, flat-topped mountain, as it was the place God would communicate his instructions to his prophet ...
Marinovich, Greg
core +1 more source
Trajectory Optimization with Constraints Using Neural Networks and Genetic Algorithms
AerospaceImproving the flight trajectory in climb phases, such as in the continuous climb operation, has the potential to reduce fuel consumption. In this paper, we propose an approach that combines a neural network and genetic algorithms to determine the fuel ...
Haruto Taguchi, Eri Itoh
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source