Mutations in apicoplast rRNA genes are associated with clindamycin resistance and impair the ability of malaria parasites to infect mosquitoes [PDF]
Drug resistance hampers malaria treatment and control. Resistance to nearly all clinically used antimalarials has emerged and spread globally. With multi-drug-resistant parasites now on the rise, understanding resistance mechanisms and their ability to ...
Jessica L. Home +3 more
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Estradiol-Induced Modulation of Clindamycin Susceptibility in Mono- and Dual-Species Biofilms of Lactobacillus gasseri and Cutibacterium acnes: An In Vitro Model Study [PDF]
This pilot study investigated the effects of estradiol and clindamycin on mono- and dual-species biofilms of selected reference and clinical isolates of Lactobacillus gasseri and Cutibacterium acnes, including one vaginal isolate of C. acnes.
Varvara P. Pavlova +9 more
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Consciousness Disturbances Reported With Clindamycin Versus Cefazolin in Surgical Patients: A Global Pharmacovigilance Analysis Using VigiBase [PDF]
Clindamycin is a common β‐lactam substitute for surgical prophylaxis. Whether peri‐operative disturbances in consciousness are disproportionately reported with clindamycin in global pharmacovigilance data remains unclear.
Kazuki Nishida +8 more
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Clindamycin as an Alternative Option in Optimizing Periodontal Therapy
Periodontal disease is an oral infectious and inflammatory disease caused by microorganisms that determine the host-mediated destruction of soft and hard periodontal tissues, which ultimately leads to tooth loss. Periodontitis affects a large part of the
Ionut Luchian +3 more
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An alternative synthesis of clindamycin [PDF]
A novel synthesis of clindamycin from lincomycin using N-chlorosuccinimide and triphenylphosphine is reported. This results in high yields and avoids the use of tetrachloromethane employed in the current manufacturing process.
Bowden Keith, Stevens Graham P.
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Background Using a three-pronged acne treatment approach—combining an antibiotic, antimicrobial agent, and retinoid—may provide greater efficacy than monad or dyad treatments.
Zoe D. Draelos +6 more
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DOI: http://dx.doi.org/10.3126/njdvl.v11i1.7932 Nepal Journal of Dermatology, Venereology & Leprology Vol.11(1) 2013 pp.29 ...
S Paudel, S Agrawal, TK Dhali
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Background and Objectives. Antibiotic regimen optimization is a major concern in post extraction sequelae management following third molar surgery, mostly owing to the absence of universal guidelines.
Anna Janas-Naze +4 more
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Clindamycin Efficacy for Cutibacterium acnes Shoulder Device-Related Infections
Clindamycin is an antibiotic with high bioavailability and appropriate bone diffusion, often proposed as an alternative in guidelines for C. acnes prosthetic joint infections. We aimed to evaluate the efficacy of clindamycin in the treatment of C.
Audrey Courdurié +7 more
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Erythromycin or Clindamycin – is it Still an Empirical Therapy against Streptococcus agalactiae in Patients Allergic to Penicillin? [PDF]
Retrospective analysis of Streptococcus agalactiae antibiotic susceptibility isolated in 2010–2013 was performed. Penicillin was still the first-line antibiotic.
Piotr Leszczyński +4 more
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