Results 211 to 220 of about 85,984 (289)

Serum Proteomic Profiling Uncovers Dysregulated Keratinisation and Immune‐Related Pathways in Hidradenitis Suppurativa

open access: yesExperimental Dermatology, Volume 35, Issue 4, April 2026.
ABSTRACT Hidradenitis suppurativa (HS) is an autoinflammatory keratinisation disease affecting the pilosebaceous unit and hallmarked by a complex and multifactorial pathogenesis. Although genomic and transcriptomic investigations have substantially advanced our understanding of key mechanisms underlying HS pathogenesis, proteomic studies remain limited,
Chiara Moltrasio   +9 more
wiley   +1 more source

Histopathology, Diagnosis, Management and Treatment Outcomes of Cemental Tears: A Retrospective Observational Cohort Study

open access: yesInternational Endodontic Journal, Volume 59, Issue 4, Page 614-631, April 2026.
ABSTRACT Introduction Diagnosing cemental tears remains challenging, and treatment outcomes can be unpredictable; recommendations for their diagnosis and management are primarily based on case reports and anecdotal experience. Although a classification has been developed for cemental tears, its clinical applicability and importance have yet to be ...
Angeline Hui Cheng Lee   +3 more
wiley   +1 more source

Repurposing caspofungin as a small-molecule inhibitor of Clostridium perfringens α-toxin for treatment of gas gangrene. [PDF]

open access: yesCommun Med (Lond)
Takehara M   +10 more
europepmc   +1 more source

Two‐Stage Surgical Management of Anogenital Hidradenitis Suppurativa in Patients on Biologic Therapy: A Retrospective Case Series

open access: yesInternational Wound Journal, Volume 23, Issue 4, April 2026.
ABSTRACT Hidradenitis suppurativa is a chronic inflammatory skin disorder causing painful nodules, abscesses and scarring, with the anogenital region presenting particular functional and reconstructive challenges. Although biologic therapy is commonly used in moderate to severe disease, its limitations highlight the role of surgery in advanced cases ...
Nino Fuchs   +3 more
wiley   +1 more source

Clinical characterization of an <i>emm1</i>-dominant group A <i>Streptococcus</i> outbreak in Chile in the context of the previous 6 years. [PDF]

open access: yesFront Cell Infect Microbiol
Valenzuela G   +9 more
europepmc   +1 more source

Epidemiology, Management, and Alarmingly High Mortality of Burn Patients: A Retrospective Analysis From a Resource‐Limited Tertiary Centre in Syria

open access: yesInternational Wound Journal, Volume 23, Issue 4, April 2026.
ABSTRACT Burn injuries pose a significant challenge in resource‐limited settings, particularly during humanitarian crises. This study examines the epidemiology, management, and outcomes of burn patients at a tertiary hospital in Damascus, Syria, from 2021 to 2024.
Lorieh Domat   +6 more
wiley   +1 more source

Towards the development of upgrade criteria for the treatment of hidradenitis suppurativa with biologics

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 40, Issue 4, Page 658-669, April 2026.
Forty‐three HS specialists from 22 European countries reported adherence to HS guidelines and use of antibiotics before biologics despite limited efficacy and rapid relapse (49% within 1–3 months). Seventy‐nine per cent supported short‐term biologics for severe Hurley I disease.
Georgios Nikolakis   +41 more
wiley   +1 more source

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