Results 101 to 110 of about 10,946,773 (345)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Genitofemoral nerve course and branching variations: what we see during laparoscopic extended pelvic lymph-node dissection in radical prostatectomy for prostate cancer, and how to avoid intraoperative lesions: a retrospective analysis

open access: yesFolia Morphologica
BACKGROUND: The genitofemoral nerve is the most variable nerve of the lumbar plexus in terms of its course and bifurcation, and therefore it must be taken into consideration during extended pelvic lymph node dissection.
Flavio Forte   +9 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Challenges of the 21st Century: Part 1 - Diagnostic, prognostic and interventional anatomy

open access: yes, 2021
Gross anatomy is a fundamental component of the medical school curriculum, anatomy research and cardiology. There remain new and continued applications of anatomical research that are critical to maintain (and improve) the levels of medical care in ...
Nguyen, Thach, Talarico, Ernest
core  

Proposal for an Expanded Classification of the Superficial Musculoaponeurotic System (SMAS) in the Human Forehead, Based on Anatomical and Microscopic Study

open access: yesLife
Introduction. The superficial musculoaponeurotic system (SMAS) is fundamental for facial soft tissue support and surgical rejuvenation. Although its morphology in the midface and neck is well characterized, the structure of its cranial extension to the ...
Yuriy L. Vasil’ev   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Formaldehyde-related clinical symptoms reported by medical students during gross anatomy cadaver dissection

open access: yes, 2016
Introduction . Formaldehyde is a noxious gas used as a tissue preservative of cadavers in autopsy rooms. Therefore, exposure to higher concentrations applies particularly to laboratory staff, anatomists and medical students.
Anna Torres   +4 more
core   +1 more source

Prevalence of Radial Artery Variants and Their Relationship with Clinical Considerations of the Antebrachial Region: Systematic Review and Meta-Analysis

open access: yesDiagnostics
Background: The radial artery (RA) is one of the terminal branches of the brachial artery, extending along the lateral forearm, crossing the anatomical snuffbox, and contributing to the palmar arches. Anatomical variations in the RA are of great clinical
Juan Sanchis-Gimeno   +14 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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