Results 1 to 10 of about 126,051 (198)

Key measurement concepts and appropriate clinical outcome assessments in pediatric achondroplasia clinical trials

Orphanet Journal of Rare Diseases, 2022
Background This study aimed to identify fit-for-purpose clinical outcome assessments (COAs) to evaluate physical function, as well as social and emotional well-being in clinical trials enrolling a pediatric population with achondroplasia.
Natalie V. J. Aldhouse, Helen Kitchen, Chloe Johnson, Chris Marshall, Hannah Pegram, Sheryl Pease, Sam Collins, Christine L. Baker, Katherine Beaverson, Chandler Crews, Jill Massey, Kathleen W. Wyrwich   +11 more
doaj   +1 more source

Content validity of a newly developed observer-reported measure for pediatric asthma in children aged 2–5 years

Journal of Patient-Reported Outcomes, 2022
Background An observer-reported outcome (ObsRO) measure assessing both symptom control and health-related quality of life (HRQoL) in children with asthma younger than 6 years is lacking. The objective of this study was to evaluate the content validity of
Yi Zhang, Jennifer L. Clegg, Shannon Keith, Shehan McFadden, Tara Symonds, Rajesh Kumar, Asif H. Khan, Siddhesh Kamat, Jingdong Chao   +8 more
doaj   +1 more source

A decade comparison of regulatory decision patterns for oncology products to all other non‐oncology products among Swissmedic, European Medicines Agency, and US Food and Drug Administration

Clinical and Translational Science, 2023
Consensus of regulatory decisions on the same Marketing Authorization Application (MAA) are critical for stakeholders. In this context, regulatory decision patterns from the Swissmedic (SMC), the US Food and Drug Administration (FDA), and the European ...
Ulrich‐P. Rohr, Mario Iovino, Leonie Rudofsky, Qiyu Li, Stephanie Juritz, Arunas Gircys, Oliver Wildner, Magda Bujar, Claus Bolte, Simon Dalla Torre di Sanguinetto, Anita Wolfer   +10 more
doaj   +1 more source

Utility of transcranial magnetic stimulation in the assessment of spinal cord injury: Current status and future directions

Frontiers in Rehabilitation Sciences, 2022
Comprehensive assessment following traumatic spinal cord injury (SCI) is needed to improve prognostication, advance the understanding of the neurophysiology and better targeting of clinical interventions.
Tarun Arora, Naaz Desai, Steven Kirshblum, Steven Kirshblum, Steven Kirshblum, Steven Kirshblum, Robert Chen, Robert Chen, Robert Chen   +8 more
doaj   +1 more source

Has the OSCE Met Its Final Demise? Rebalancing Clinical Assessment Approaches in the Peri-Pandemic World

Frontiers in Medicine, 2022
The Objective Structured Clinical Examination (OSCE) has been traditionally viewed as a highly valued tool for assessing clinical competence in health professions education.
Bunmi S. Malau-Aduli, Karina Jones, Shannon Saad, Cassandra Richmond   +3 more
doaj   +1 more source

Tools for the Assessment of Risk-Taking Behavior in Older Adults with Mild Dementia: A Cross-Sectional Clinical Study

Brain Sciences, 2023
Diseases such as Alzheimer’s cause an alteration of cognitive functions, which can lead to increased daily risk-taking in older adults living at home. The assessment of decision-making abilities is primarily based on clinicians’ global analysis.
Charline Compagne, Damien Gabriel, Lénaïc Ferrero, Eloi Magnin, Thomas Tannou   +4 more
doaj   +1 more source

Examining Whether Onfield Motor Incoordination Is Associated With Worse Performance on the SCAT5 and Slower Clinical Recovery Following Concussion

Frontiers in Neurology, 2021
Objective: To examine the relationship between video-identified onfield motor incoordination, the acute assessment of concussion, and recovery time during three seasons of National Rugby League (NRL) play.Methods: Blows to the head (“head impact events”)
Grant L. Iverson, Grant L. Iverson, Grant L. Iverson, Grant L. Iverson, Grant L. Iverson, Ryan Van Patten, Ryan Van Patten, Ryan Van Patten, Andrew J. Gardner, Andrew J. Gardner   +9 more
doaj   +1 more source

Working memory training is associated with long term attainments in math and reading comprehension

Frontiers in Psychology, 2015
Training working memory (WM) using computerized programs has been shown to improve functions directly linked to WM such as following instructions and attention.
Stina eSöderqvist, Sissela eBergman Nutley   +1 more
doaj   +1 more source

Nurses' Experiences and Perceptions of two Early Warning Score systems to Identify Patient Deterioration—A Focus Group Study

Nursing Open, 2021
Aims To explore Registered Nurses' experiences and perceptions with National Early Warning Score and Individual Early Warning Score to identify patient deterioration. Design A qualitative exploratory design. Methods Six focus groups were conducted at six
Caroline S. Langkjaer, Dorthe G. Bove, Pernille B. Nielsen, Kasper K. Iversen, Morten H. Bestle, Gitte Bunkenborg   +5 more
doaj   +1 more source

Psychometric properties of a clinical assessment tool in the postgraduate midwifery programme, Botswana

Curationis, 2023
Background: The psychometric properties of a clinical assessment tool used in the postgraduate midwifery programme in Botswana have not been evaluated.
Itumeleng Rasetshwane, Nombulelo V. Sepeng, Ramadimetja S. Mooa   +2 more
doaj   +1 more source