Results 241 to 250 of about 453,652 (299)

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source

Association of Previous Clinical Breast Examination With Reduced Delays and Earlier-Stage Breast Cancer Diagnosis Among Women in Peru.

JAMA Oncol, 2017
Romanoff A, Constant TH, Johnson KM, Guadiamos MC, Vega AMB, Zunt J, Anderson BO.   +6 more
europepmc   +1 more source

A longitudinal observational study of male referrals and adherence to imaging guidelines: a single centre experience in 148 patients. [PDF]

Front Oncol
Pestrin O, Agilinko J, Basharat SH, Ali T, Wahab T.   +4 more
europepmc   +1 more source

Multicenter prospective study of dedicated breast positron emission tomography (dbPET) for breast cancer: examination in preoperative patients. [PDF]

BMC Med Imaging
Satou Y, Nakagami Y, Suga K, Yamaguchi Breast Cancer Study Group (YBC).   +3 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Optimization of Clinical Breast Examination

The American Journal of Medicine, 2010
Breast examination is necessary for evaluation of the 8% to 17% of cancers missed by mammograms, but it is being done less often and less effectively. To improve the use of breast examination, we tested whether a technique to focus attention could improve the call rate (the percent of examinations leading to further evaluation), a measure of quality ...
William H, Goodson, Thomas K, Hunt, Julia N, Plotnik, Dan H, Moore   +3 more
openaire   +2 more sources

Screening clinical breast examination

Surgical Clinics of North America, 2003
Evidence suggests that CBE detects most breast cancers found by mammograms, and also some that mammograms miss, particularly in younger women. Recent estimates suggest that screening CBE has a sensitivity of about 54% and a specificity of about 94%. Yet, the impact of screening CBE on breast cancer mortality is still not clear, as there are no trials ...
openaire   +2 more sources

The role of clinical breast examination and breast self-examination

Preventive Medicine, 2011
The efficacy of screening by clinical breast examination (CBE) and/or breast self-examination (BSE) is reviewed using indirect evidence from randomized breast screening trials and that from observational studies. In countries where breast cancer is diagnosed at an advanced stage, screening by CBE with the teaching of BSE as an integral component will ...
Anthony B, Miller, Cornelia J, Baines
openaire   +2 more sources