Results 41 to 50 of about 7,211,206 (134)

Delivery Systems for Therapeutic Genome Editing: Challenges, Innovations, and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Schematic illustration of four emerging CRISPR–Cas delivery platforms defined by distinct design principles and structural features: virus‐mimicking nanosystems (e.g., VLPs), cell‐derived extracellular vesicles, cell‐penetrating peptides, and stimuli‐responsive scaffolds. These platforms enable spatiotemporally controlled delivery of RNPs, mRNA, or DNA
Meijia Yang, Yiqiong Song, Ziyang Wang, Ke Chao, Lifeng Li, Xu Zhang, Xiaoran Duan, Chenglong Yu, Ruyue Xue, Jie Zhao   +9 more
wiley   +1 more source

Breast Ultrasound Following a Positive Clinical Breast Examination: Does It Have a Role in Low- and Middle-Income Countries?

Journal of Global Radiology, 2015
Purpose: Breast cancer is the most common cancer among women worldwide, with an estimated 1.7 million new cases occurring in 2012. The majority of cases and deaths occur in low- and middle-income countries (LMICs), where population-based mammography ...
Vivien Tsu, John R Scheel, Amie Bishop, Marjorie Murray, Bernhard Weigl, Constance D Lehman   +5 more
doaj   +1 more source

Breast cancer surveillance in BRCA positive Sri Lankan women: health equity for a high-risk group at a limited resource setting

BMC Women's Health, 2023
Background BRCA1 and BRCA2 pathogenic variants account for 90% of hereditary breast malignancies, incurring a lifetime breast cancer risk of 85% and 40–45% respectively, in affected individuals.
Udari Apsara Liyanage, Nirmala Dushyanthi Sirisena, Pushpika Chathuranga Deshapriya, Vajira Harshadeva Weerabaddana Dissanayake   +3 more
doaj   +1 more source

Knowledge, Attitude and Practice of Breast Cancer Screening in Medical and Non-Medical Females Students of Lahore, Pakistan

Proceedings, 2021
Introduction: Breast cancer is the most common cancer in women all over the world and a leading cause of death in women of Pakistan. Programs promoting awareness about breast cancer, breast self-examination (BSE), clinical breast examination (CBE) and ...
Jawaria Ghazanfar, Ayesha Khalil, Aniqua Tahir, Muhammad Imran Anwar, Hina Mahmood, Ayesha Humayun   +5 more
doaj   +1 more source

ER and HER2 expression are positively correlated in HER2 non-overexpressing breast cancer. [PDF]

, 2012
INTRODUCTION: Estrogen receptor-α (ER) and human epidermal growth factor receptor 2 (HER2) positivity are inversely correlated by standard criteria. However, we investigated the quantitative relation between ER and HER2 expression at both RNA and protein
Yarnold, J, Drury, Suzanne, Barrett-Lee, P, Hills, Margaret, Salter, J, Lawrence, D, Harnett, AM, Cuzick, J, Earl, H, Sestak, I, Ma, NCRIABCT, Georges Sumo, A'Hern, R, Sestak, Ivana, Barrett-Lee, Peter Jeffrey, Dowsett, M, A'Hern, Roger, Robinson, A, Perren, T, Johnson, L, Harris, Adrian, George, WD, Bliss, JM, Dodwell, D, null null, Peter Barrett-Lee, Price, D, Foster, L, Poole, C, Isabel Pinhel, Suzanne Drury, Fernando, I, Dowsett, Mitch, Cuzick, Jack, Judith M Bliss, Barrett-Lee, Peter, Sumo, G, Raina, V, Hills, M, Roger A'Hern, Ivana Sestak, Adrian Harris, Janine Salter, Jack Cuzick, Bliss, Judith M., Brunt, AM, Peto, J, Drury, S, Bliss, Judith M, Sumo, Georges, Margaret Hills, Mitch Dowsett, Pinhel, Isabel, Harris, A, NCRI Adjuvant Breast Cancer Trial Management Group, Bliss, M, Pinhel, I, Salter, Janine   +57 more
core   +2 more sources

The Effect of Education about Importance of Clinical Breast Examination on Attendance of Kermanian Teacher Women for Examination

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2004
Introduction: Secondry Prevention is Very important in breast cancer because when treatment is started,the breast mass will have smaler size. One of the most important way For Secondry Prevention of breast cancer is examination by Physician or health ...
S Mohammad Ali Zadeh, Zh Mirlashari, M Azizzaheh Forozi   +2 more
doaj  

Breast Cancer Early Detection in Eswatini: Evaluation of a Training Curriculum and Patient Receipt of Recommended Follow-Up Care

JCO Global Oncology, 2021
PURPOSEBreast cancer (BC) is detected at late stages in sub-Saharan Africa. We piloted a BC early-detection program in Eswatini aimed at increasing breast health knowledge and clinical skills.
Daniel S. O'Neil, Sifiso Nxumalo, Cebisile Ngcamphalala, G Tharp, Judith S. Jacobson, Harriet Nuwagaba-Biribonwoha, Xolisile Dlamini, Lydia E. Pace, Alfred I. Neugut, Tiffany G. Harris   +9 more
doaj   +1 more source

Implementation of a clinical breast exam and referral program in a rural district of Pakistan

BMC Health Services Research
Background The role of clinical breast examination (CBE) for early detection of breast cancer is extremely important in lower-middle-income countries (LMICs) where access to breast imaging is limited.
Russell Seth Martins, Aiman Arif, Sahar Yameen, Shanila Noordin, Taleaa Masroor, Shah Muhammad, Mukhtiar Channa, Sajid Bashir Soofi, Abida K. Sattar   +8 more
doaj   +1 more source

Clinical Utility of a Hand-Held Scanner for Breast Cancer Early Detection and Patient Triage

JCO Global Oncology, 2020
PURPOSE Globally, breast cancer represents the most common cause of cancer death among women. Early cancer diagnosis is difficult in low- and middle-income countries, most of which are unable to support population-based mammographic screening.
Julie M. Clanahan, Sanjana Reddy, Robyn B. Broach, Anne F. Rositch, Benjamin O. Anderson, E. Paul Wileyto, Brian S. Englander, Ari D. Brooks   +7 more
doaj   +1 more source

Factors associated with positive cancer screening for the uterine cervix and breast in Jakarta Province, Indonesia: a cross-sectional study

BMC Cancer, 2022
Background In many middle-income countries, cancer incidence and mortality are rapidly increasing, but data for developing a strategy of cancer control are rarely collected or analyzed. This study aimed to identify factors associated with positive cancer
Lady Margaretha Febriany Sirait, Nobuyuki Hamajima, Yunosuke Suzuki, Endang Sri Wahyuningsih, Dwi Oktavia, Widyastuti, Souphalak Inthaphatha, Kimihiro Nishino, Eiko Yamamoto   +8 more
doaj   +1 more source