Results 151 to 160 of about 3,618,792 (267)

Clinical Characteristics and Treatment Patterns in Patients With Vitiligo.

JAMA Dermatol
Adiri R, Gauthier G, Kurosky SK, Sadrarhami M, Bell G, Fiasconaro M, Zhou Y, Rosmarin D, Elbuluk NM, Pandya AG, Hamzavi I.   +10 more
europepmc   +1 more source

Prevalence and Clinical Characteristics of Isolated Intraventricular Hemorrhage. [PDF]

Cerebrovasc Dis Extra
Arakaki Y, Miwa K, Shiozawa M, Ogawa A, Inutsuka R, Usui R, Iwamoto S, Nakahara J, Toyoda K, Ihara M, Koga M.   +10 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Clinical characteristics, treatment, and outcomes of Oxaliplatin-induced immune thrombocytopenia. [PDF]

Front Immunol
Huang N, Liu Z, Li R, Lei H, Liu X.
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The genetic and clinical characteristics of oculopharyngeal muscular dystrophy patients in Israel. [PDF]

Orphanet J Rare Dis
Ben-David M, Greenbaum L, Nikitn V, Zvulunov A, Charas H, Divon N, Barkan T, Chorin O, Reznik-Wolf H, Zloto O, Benyamini L, Shelly S, Dori A.   +12 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Clinical Characteristics of Combat Crewmen.

JAMA Netw Open
Powell JR, Lippa SM, McKenzie-Hartman TL, Rhodes CS, Pickett TC, Srikanchana R.   +5 more
europepmc   +1 more source

Clinical Characteristics and Technical Outcomes of Microballoon Catheter-assisted Partial Splenic Embolization. [PDF]

In Vivo
Ishikawa T, Goto M, Sato R, Natsui H, Endo S, Jimbo R, Yamazaki S, Iwasawa T, Kobayashi Y, Sano T, Honma T.   +10 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source