Results 91 to 100 of about 497,459 (309)

Self testing, an emerging component of clinical chemistry.

open access: yesClinical Chemistry, 1984
Abstract Self testing as a phase of health delivery has been utilized for approximately 70 years, but within the last two decades there has been an increasing interest in and use of self testing. The practice of self testing has a sound basis, which involves medical relevancy, cost containment, and convenience.
A H, Free, H M, Free
openaire   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Urine Specimens from Pregnant and Nonpregnant Women Inhibitory to Amplification of \u3cem\u3eChlamydia trachomatis\u3c/em\u3e Nucleic Acid by PCR, Ligase Chain Reaction, and Transcription-Mediated Amplification: Identification of Urinary Substances Associated with Inhibition and Removal of Inhibitory Activity [PDF]

open access: yes, 1998
The presence of endogenous amplification inhibitors in urine may produce false-negative results for the detection of Chlamydia trachomatis nucleic acids by tests such as PCR, ligase chain reaction (LCR), and transcription-mediated amplification (TMA ...
Chernesky, Max A.   +7 more
core   +1 more source

Biosensor assay for determination of haptoglobin in bovine milk [PDF]

open access: yes, 2006
Despite more than 30 years of research into mastitis diagnostics, there are few alternatives to the somatic cell count (SCC) in practical use for identification of cows with subclinical mastitis.
Björk, Lennart   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

New trends for metal complexes with anticancer activity [PDF]

open access: yes, 2008
Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design of new drugs. This has, for instance, led to the clinical application of chemotherapeutic agents for cancer treatment, such as cisplatin. The use of cisplatin is,
Ang   +56 more
core   +1 more source

Single Intramuscular-dose Toxicity of Anti-inflammatory Pharmacopuncture in Rats

open access: yesJournal of Pharmacopuncture, 2013
Objectives: This study was performed to analyze the toxicity of the test substance, anti-inflammatory pharmacopuncture (AIP), when used as a single intramuscular-dose in 6-week-old, male and female Sprague-Dawley rats and to find the lethal dose ...
Jung Da-jung   +8 more
doaj   +1 more source

Autoverification in a core clinical chemistry laboratory at an academic medical center

open access: yesJournal of Pathology Informatics, 2014
Background: Autoverification is a process of using computer-based rules to verify clinical laboratory test results without manual intervention. To date, there is little published data on the use of autoverification over the course of years in a clinical ...
Matthew D Krasowski   +13 more
doaj   +1 more source

Influence of hemolysis on routine clinical chemistry testing

open access: yesJournal of Chittagong Medical College Teachers' Association, 1970
doi: 10.3329/jcmcta.v18i1.3814Journal of Chittagong Medical College Teachers' Association 2007: 18(1):12 ...
MA Mazed   +5 more
openaire   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

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