Results 201 to 210 of about 497,459 (309)

Biochemical profiling provides a low-cost and globally accessible method to detect falsified vaccines and insulin. [PDF]

Sci Rep
Brook J, Bharucha T, Arman BY, Caillet C, Morris S, Taylor-Siddons M, Fernandez LG, Walsby-Tickle J, Legge I, Banerjee S, Deats M, Jena R, Ranade DS, Chunekar SR, Patil KD, Gairola S, Dunachie S, Merchant HA, Stokes R, Kuwana R, Maes A, Gilbert S, McCullagh J, Matousek P, Zitzmann N, Newton PN, Gangadharan B, James T.   +27 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Prescription Support Practice for Pharmacy Students: Pre-Post Educational Intervention Study.

JMIR Med Educ
Aizawa F, Yagi K, Higashionna T, Hamano H, Takahashi S, Zamami Y, Shinomiya K, Niimura T, Goda M, Kawada K, Ishizawa K.   +10 more
europepmc   +1 more source

Decentralizing care for cutaneous leishmaniasis and other skin diseases to primary health facilities in Southern Ethiopia: What are the needs? [PDF]

BMC Infect Dis
Tadesse D, Henten SV, Batire S, Woge MT, Degaga TS, Merdekios B, Abrams S, Hailu A, Geertruyden JV, Griensven JV, Pareyn M.   +10 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Nonalcoholic Fatty Liver Disease Status and Its Associated Factors Among Patients With Type 2 Diabetes Mellitus in Adama Hospital Medical College, South Eastern Ethiopia: A Cross-Sectional Study. [PDF]

Health Sci Rep
Feyisa MS, Ambachew S, Mebratie AF, Ali BE, Asefa RH, Asefa EC, Asmamaw MG, Fetene G.   +7 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Relationship between pain, functionality, and body composition in patients with fibromyalgia: cross-sectional study. [PDF]

Front Med (Lausanne)
Úbeda-D'Ocasar E, Mayoral-Gonzalo N, Pedauyé-Rueda B, Daguerre-Garrido A, Ojedo-Martín C, Fernández-Aceñero MJ, Hervás-Pérez JP, Cimadevilla-Fernández-Pola E.   +7 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

"Universal health coverage and priority diseases diagnostics: a case study of Essential Package of Health Services from Pakistan". [PDF]

Lancet Reg Health Southeast Asia
Zeeshan M, Shakoor S, Siddiqui AR, Hasan R.   +3 more
europepmc   +1 more source