Results 71 to 80 of about 497,459 (309)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
The effects of zinc sulfate on ethyl glucuronide immunoassay urine testing [PDF]
, 2016 Published research in the Journal of Analytical Toxicology and the American Society for Clinical Pathology has confirmed that the presence of Zinc Sulfate in adulterated urine samples can influence the testing results using EMIT and ELISA immunoassay ...
Cawley, Shanna Marie
core +1 more source
Grid Added Value to Address Malaria [PDF]
, 2006 Through this paper, we call for a distributed, internet-based collaboration to address one of the worst plagues of our present world, malaria. The spirit is a non-proprietary peer-production of information-embedding goods.
Breton, V. +3 more
core +5 more sources
The Application of Two-dimensional Centrifugation to Clinical Chemistry Testing [PDF]
Upsala Journal of Medical Sciences, 1986 We have developed a new clinical chemistry analyzer, the VISION System, which uses centrifugal force to separate whole blood, measure reagent and plasma volumes, and complete all steps required for a spectrophotometric analysis. The system is based on a multichambered test pack containing liquid reagents, which can be centrifuged in two planes oriented
J T, Holen, S G, Schultz, S T, Wong
openaire +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The View of Russian Students on Whether Psychology is a Science [PDF]
, 2020 The Psychology as Science Scale (Friedrich, 1996) was administered to 525 psychology students from nine Russian universities to assess their beliefs about the nature of the discipline.
Abramson, Charles I. +6 more
core
An investigation of the role of trace elements and biochemical parameters in patients with COVID-19
Northwestern Medical JournalAim: The COVID-19 pandemic is an emergent viral respiratory disease characterized by high fever and shortness of breath, and it was declared a pandemic by the World Health Organization in March 2020.
İlhan Sabancılar +5 more
doaj +1 more source
Single Intravenous-dose Toxicity of Water-soluble Carthami-flos Pharmacopuncture (WCF) in Rats
Journal of Pharmacopuncture, 2014 Objectives: This study was performed to analyze the toxicity and to find the lethal dose of the test substance Water-soluble Carthami-flos pharmacopuncture (WCF) when used as a single intravenous-dose in 6-week-old, male and female Sprague-Dawley rats ...
Da-jung Jung +4 more
doaj +1 more source
Assessing the impact of clinically relevant medicinal chemistry teaching: Learning gains from case study approach [PDF]
Brazilian Journal of Pharmaceutical SciencesConsidering the unique role of medicinal chemistry in the pharmacists’ formation, in this work we assessed the impact of medicinal chemistry teaching on the interpretation of a clinical situation using statistical and learning gain analysis.
Fernanda Domingues Lustoza +1 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source