Results 61 to 70 of about 1,285,183 (288)

"Taking your place at the table": an autoethnographic study of chaplains' participation on an interdisciplinary research team. [PDF]

, 2015
BackgroundThere are many potential benefits to chaplaincy in transforming into a "research-informed" profession. However little is known or has been documented about the roles of chaplains on research teams and as researchers or about the effects of ...
Dunn, Laura B, Hocker, Will, James, Jennifer, Kestenbaum, Allison, Morgan, Stefana, Rabow, Michael, Shields, Michele   +6 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Increased serum extrachromosomal circular DNA SORBS1circle level is associated with insulin resistance in patients with newly diagnosed type 2 diabetes mellitus

Cellular & Molecular Biology Letters
Background Extrachromosomal circular DNAs (eccDNAs) exist in human blood and somatic cells, and are essential for oncogene plasticity and drug resistance. However, the presence and impact of eccDNAs in type 2 diabetes mellitus (T2DM) remains inadequately
Xiang Kong, Shu-jun Wan, Tian-bing Chen, Lan Jiang, Yu-jie Xing, Ya-ping Bai, Qiang Hua, Xin-ming Yao, Yong-li Zhao, Hong-mei Zhang, De-guo Wang, Qing Su, Kun Lv   +12 more
doaj   +1 more source

Comparison of Knowledge Levels Required for SNOMED CT Coding of Diagnosis and Operation Names in Clinical Records [PDF]

Healthcare Informatics Research, 2012
ObjectivesCoding Systematized Nomenclature of Medicine, Clinical Terms (SNOMED CT) with complex and polysemy clinical terms may ask coder to have a high level of knowledge of clinical domains, but with simpler clinical terms, coding may require only ...
Shine Young Kim, Hyung Hoi Kim, Kyung Hwa Shin, Hwa Sun Kim, Jae Il Lee, Byung Kwan Choi   +5 more
doaj   +1 more source

Phage Selective Pressure Reduces Virulence of Hypervirulent Klebsiella pneumoniae Through Mutation of the wzc Gene

Frontiers in Microbiology, 2021
Hypervirulent Klebsiella pneumoniae (hvKp), one of the major community-acquired pathogens, can cause invasive infections such as liver abscess. In recent years, bacteriophages have been used in the treatment of K.
Lingjie Song, Xianggui Yang, Jinwei Huang, Xiaokui Zhu, Guohui Han, Yan Wan, Ying Xu, Guangxin Luan, Xu Jia   +8 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

M2 macrophage exosome-derived lncRNA AK083884 protects mice from CVB3-induced viral myocarditis through regulating PKM2/HIF-1α axis mediated metabolic reprogramming of macrophages

Redox Biology
Viral myocarditis (VM) is a clinically common inflammatory disease. Accumulating literature has indicated that M2 macrophages protect mice from Coxsackievirus B3 (CVB3)-induced VM.
Yingying Zhang, Liangyu Zhu, Xueqin Li, Chang Ge, Weiya Pei, Mengying Zhang, Min Zhong, Xiaolong Zhu, Kun Lv   +8 more
doaj   +1 more source

Validity of discharge ICD-10 codes in detecting the etiologies of endogenous Cushing’s syndrome

Endocrine Connections, 2019
Objective: To investigate the validity of discharge ICD-10 codes in detecting the etiology of endogenous Cushing’s syndrome (CS) in hospitalized patients.
Jingya Zhou, Meng Zhang, Lin Lu, Xiaopeng Guo, Lu Gao, Weigang Yan, Haiyu Pang, Yi Wang, Bing Xing   +8 more
doaj   +1 more source

Parents‘ and healthcare professionals’ perception toward the introduction of a new fully liquid hexavalent vaccine in the Malaysian national immunization program: a cross-sectional study instrument development and its application

Frontiers in Immunology, 2023
A newly developed fully liquid hexavalent vaccine that comprises six antigens for Diphtheria, Tetanus, acellular Pertussis, Inactivated Poliomyelitis, Haemophilus Influenza type b., and Hepatitis B, is proposed to be introduced in the Malaysian national ...
Lama Al Bashir, Lama Al Bashir, Aniza Ismail, Aniza Ismail, Syed Mohamed Aljunid, Syed Mohamed Aljunid, Syed Mohamed Aljunid, Syed Mohamed Aljunid   +7 more
doaj   +1 more source

Battling on the Home Front: Posttraumatic Stress Disorder and Conflict Behavior Among Military Couples [PDF]

, 2017
This study evaluated interpersonal behavior differences among male military service members with and without PTSD and their female partners. Couples (N = 64) completed a 17-minute videotaped conflict discussion, and their interaction behavior was coded ...
Caska-Walace, Catherine, Knobloch-Fedders, Lynne M., Renshaw, Keith, Smith, Timothy W.   +3 more
core   +2 more sources