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Clinical and molecular diagnosis of pathologic complete response in rectal cancer

Expert Review of Molecular Diagnostics, 2015
The current standard approach to locally advanced rectal cancer involves pre-operative chemoradiotherapy followed by total mesorectal excision. This practice is supported by several studies that have demonstrated superior local control with this approach.
Prachi M, Patel   +2 more
openaire   +2 more sources

Delayed clinical complete response to intensity-modulated radiotherapy in nasopharyngeal carcinoma

Oral Oncology, 2017
Twelve weeks after radiotherapy is the recommended time-point for assessing tumor response in nasopharyngeal carcinoma (NPC); however, regression after 12 weeks remains unclear. We explored NPC regression and the prognosis of patients with delayed clinical complete response (cCR).MRI images of 556 NPC patients treated with intensity-modulated ...
Wen-Fei Li   +8 more
openaire   +2 more sources

Management of Low Rectal Cancer After Complete Clinical Response

2018
Neoadjuvant chemoradiation has become one of the preferred initial treatment strategies for the management of distal rectal cancer. Development of significant or even complete tumor regression following this treatment strategy may be considerably frequent depending on baseline disease stage and specific chemoradiation regimen.
Angelita Habr-Gama   +4 more
openaire   +1 more source

Nonoperative Management of Rectal Cancer With Complete Clinical Response After Neoadjuvant Therapy

Annals of Surgery, 2012
Nonoperative management (NOM) of rectal cancer after a complete clinical response (cCR) to neoadjuvant therapy is controversial. In this article, we retrospectively reviewed the outcomes of patients managed with selective NOM after a cCR to neoadjuvant treatment and compared these with patients who underwent standard rectal resection with a ...
James D, Smith   +8 more
openaire   +2 more sources

Clinical Prediction of Pathological Complete Response After Preoperative Chemoradiotherapy for Rectal Cancer

Diseases of the Colon & Rectum, 2013
The clinical pretreatment factors that accurately predict response to chemoradiation in rectal cancer are not currently known.The aim of this study is to evaluate the clinical factors associated with a pathological complete response after preoperative chemoradiotherapy for rectal cancer.This study is a retrospective review of prospectively collected ...
Jung Wook, Huh   +2 more
openaire   +2 more sources

Su620 CAN CLINICAL COMPLETE RESPONSE PREDICT PATHOLOGIC COMPLETE RESPONSE FOLLOWING NEOADJUVANT CHEMORADIATION FOR ESOPHAGEAL CANCER?

Gastroenterology, 2021
Tyler L. Holliday   +12 more
openaire   +1 more source

Is There a Correlation Between Clinical Complete Response and Pathological Complete Response After Neoadjuvant Chemoradiotherapy for Esophageal Squamous Cell Cancer?

Annals of Surgical Oncology, 2015
The aim of this study was to investigate the correlation between clinical complete response (cCR) and pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (CRT) for esophageal squamous cell cancer (ESCC).Between May 2001 and April 2013, a total of 158 patients with thoracic ESCC treated with neoadjuvant CRT followed by surgery were ...
Shi-Liang, Liu   +8 more
openaire   +2 more sources

Clinical outcome after complete response with immunotherapy in hepatocellular carcinoma.

Journal of Clinical Oncology
573 Background: Immunotherapy has shown great efficacy in hepatocellular carcinoma (HCC). No clear consensus exists on when to stop the immune checkpoint inhibitor (ICI) after complete response (CR), and clinical course after stopping ICI remains unknown.
Pin-Jung Chen   +11 more
openaire   +1 more source

Functional outcomes after TEM in patients with complete clinical response after neoadjuvant chemoradiotherapy

Surgical Endoscopy, 2016
In patients who exhibit a complete clinical response after radio-chemotherapy for rectal cancer, the standard surgical approach might constitute overtreatment. The aim of this study is to analyse the outcomes of anorectal function and quality of life after transanal endoscopic microsurgery (TEM) in irradiated patients with complete clinical response ...
Roberto, Ghiselli   +5 more
openaire   +2 more sources

Markers in Identifying Pathological Complete Response Status in Muscle Invasive Bladder Cancer Patients Who Achieved Clinical Complete Response After Neoadjuvant Chemotherapy

Clinical Genitourinary Cancer
Prior research has demonstrated a discrepancy between pathologic and clinical staging in individuals with muscle-invasive bladder cancer (MIBC) following neoadjuvant chemotherapy (NAC). These findings were the major reasons for the under-usage of the bladder preservation strategy.
Chengri Piao   +3 more
openaire   +2 more sources

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