Results 101 to 110 of about 63,594 (281)
Advanced Intelligent Discovery, EarlyView.Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
A Fast Healthcare Interoperability Resources (FHIR) layer implemented over i2b2
BMC Medical Informatics and Decision Making, 2017 Background Standards and technical specifications have been developed to define how the information contained in Electronic Health Records (EHRs) should be structured, semantically described, and communicated.
Abdelali Boussadi, Eric Zapletal
doaj +1 more source
Digital curation and the cloud [PDF]
, 2012 Digital curation involves a wide range of activities, many of which could benefit from cloud deployment to a greater or lesser extent. These range from infrequent, resource-intensive tasks which benefit from the ability to rapidly provision resources
Aitken, B. +3 more
core
Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art
Advanced Intelligent Discovery, EarlyView.Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser +6 more
wiley +1 more source
Tracking provenance in clinical data warehouses for quality management
International Journal of Medical InformaticsData provenance, which documents the origin, history, and transformations of data, can enhance the reproducibility of processing workflows and help to address errors and quality issues. In this work, we focus on tracking and utilizing provenance information as part of quality management in Extract-Transform-Load (ETL) processes used to build clinical ...
Marco Johns, Lena Baum, Fabian Prasser
openaire +2 more sources
A dimensional warehouse for integrating operational data from clinical trials
Database, 2019 Timely, consistent and integrated access to clinical trial data remains one of the pharmaceutical industry's most pressing needs. As part of a comprehensive clinical data repository, we have developed a data warehouse that can integrate operational data from any source, conform it to a canonical data model and make it accessible to study teams in a ...
Michael A Farnum +6 more
openaire +2 more sources
AI Powered Biobanks From Static Archives to Dynamic Discovery Engines
Advanced Intelligent Discovery, EarlyView.Large language models (LLMs) provide a potential framework for transforming biobanks from static data repositories into intelligent discovery engines. By enabling unified representation and analysis of multimodal biomedical data, LLM‐based systems facilitate dynamic risk prediction, biomarker identification, and mechanistic interpretation, thereby ...
Wenzhen Yin +5 more
wiley +1 more source
Roadmap to a Comprehensive Clinical Data Warehouse for Precision Medicine Applications in Oncology
Cancer Informatics, 2017 Leading institutions throughout the country have established Precision Medicine programs to support personalized treatment of patients. A cornerstone for these programs is the establishment of enterprise-wide Clinical Data Warehouses. Working shoulder-to-
David J Foran +10 more
doaj +1 more source
Advanced Intelligent Discovery, EarlyView.This article implements a unified human digital twin framework that integrates cutting edge actuation, sensing, simulation, and bidirectional feedback capability. The approach includes integrating multimodal sensing, AI, and biomechanical simulation into one compact system.
Tajbeed Ahmed Chowdhury +4 more
wiley +1 more source