Results 161 to 170 of about 935,725 (295)

Methodologies of legacy clinical decision support system-a review

, 2017
Information technology playing a prominent role in the field of medical by incorporating the Clinical Decision Support System(CDSS) in their routine practices.
Jawatankuasa Kerja PSM UTeM
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

How and Why Decision Models Influence Marketing Resource Allocations

We study how and why model-based Decision Support Systems (DSSs) influence managerial decision making, in the context of marketing budgeting and resource allocation.
Rangaswamy, A., Lilien, G.L., Starke, K., Bruggen, G.H. van   +3 more
core  

Agent-Based Distributed Decision Support System for Brain Tumour Diagnosis and Prognosis

, 2006
Brain tumours remain an important cause of morbidity and mortality in Europe. Diagnosis using Magnetic Resonance Imaging (MRI) is non-invasive, but only achieves 60-90% accuracy depending on the tumour type and grade.
Mier, M, Lewis, Paul, Arus, C, Robles, M, van Huffel, S, Gonzalez-Velz, H, Peet, A, Celda, B   +7 more
core  

Verification of the value of optimization of the medication-related clinical decision support system in China, a hospital-based study. [PDF]

JAMIA Open
Ran S, Gu D, Xie J, Jiang K, Yao N, Fang Z, Asakawa T, Zhang N, Fang H.   +8 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

ELECTRONIC MEDICAL RECORD - SUCCESS OR FAILURE IN THE MEDICAL DECISION FROM THE ROMANIAN HEALTH SYSTEM ? [PDF]

The investments in informational and communicational technologies in the health field represent a for of investing in human capital because health and medical services will exceed the physician – patient relationship and the improvement of the physical ...
Assist. Adina Bălan Ph. D
core  

Reliability and Feasibility Assessment of EldenCare: A Geriatric Clinical Decision Support System Pilot Study. [PDF]

Hosp Pharm
Syed J, Chalasani SH, Pereira P, Sharma A, Patil V, Ramesh M, Dayananda CM, Polumuri SK, Tank NB, Pallavi TL, Deepa T, Ghule G.   +11 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Development Process of a Clinical Decision Support System for Empiric Antibiotic Therapies in Patients With Sepsis: Case Study. [PDF]

JMIR Med Inform
Schmiegel S, Marchi H, Hege P, Elkenkamp S, Duevel J, Düsing C, Greiner W, Scholz SS, Witzke D, Tebbe JJ, Wehmeier M, Kaup O, Borgstedt R, Rehberg S, Cimiano P, Fuchs C.   +15 more
europepmc   +1 more source