Results 251 to 260 of about 8,630,835 (311)
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CLINICAL EFFICACY OF PERINDOPRIL IN HYPERTENSION
Clinical and Experimental Pharmacology and Physiology, 1992SUMMARY1. Perindopril's effectiveness in mild to moderate hypertension was evaluated in three studies.2. Perindopril was more effective than sodium restriction in reducing blood pressure, and the effects were additive.3. Perindopril was as effective as atenolol in reducing blood pressure, and was well tolerated.4.
T, Morgan, A, Anderson
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Clinical Efficacy of Eprosartan
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1999Eprosartan is a new, structurally distinct, nonbiphenyl, nontetrazole, nonpeptide, orally active angiotensin II receptor antagonist that is highly selective for the AT1 receptor. In placebo‐controlled trials, it led to a dose‐related antihypertensive response, clinically significant reductions in blood pressure and full 24‐hour blood pressure control ...
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Solifenacin: pharmacology and clinical efficacy
Expert Review of Clinical Pharmacology, 2009While antimuscarinic drug therapy has been proven to be effective in the management of patients with symptoms of overactive bladder syndrome, compliance and persistence with medication is often affected by the bothersome antimuscarinic adverse effects of dry mouth, constipation, somnolence and blurred vision.
Dudley, Robinson, Linda, Cardozo
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Comparisons of Clinical Efficacy
British Journal of Psychiatry, 1993This paper does not attempt to review the whole topic of clinical efficacy but will consider general concepts, particularly in the light of the advent of the serotonin (5-HT) uptake inhibitors (SSRIs).The aetiology of depression is complex. In most cases there is some form of predisposition based on problematical family dynamics, disordered family ...
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In silico prediction of clinical efficacy
Current Opinion in Biotechnology, 2006Drug development is a high risk and costly process, and the ability to predict clinical efficacy in silico (in a computer) can save the pharmaceutical industry time and resources. Additionally, such an approach will result in more targeted, personalized therapies.
Seth, Michelson +2 more
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Neurosurgery, 1977
When applied under the circumstances of minimal patient risk documented in this paper, implanted neuroaugmentive spinal devices are a reasonable means of therapy for selected severe pain problems. With presently developed screening techniques, in 198 patients predominantly suffering from failed back surgery syndrome, a 50% good-to-excellent result was ...
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When applied under the circumstances of minimal patient risk documented in this paper, implanted neuroaugmentive spinal devices are a reasonable means of therapy for selected severe pain problems. With presently developed screening techniques, in 198 patients predominantly suffering from failed back surgery syndrome, a 50% good-to-excellent result was ...
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Rheumatology, 1976
Ketoprofen has, over the last few years, undergone extensive clinical trials in many centres throughout the world and these are reviewed. Adequately controlled trials have established its undoubted clinical efficacy as an antirheumatic agent in all the major rheumatic diseases, and have demonstrated therapeutic potency, comparable with other ...
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Ketoprofen has, over the last few years, undergone extensive clinical trials in many centres throughout the world and these are reviewed. Adequately controlled trials have established its undoubted clinical efficacy as an antirheumatic agent in all the major rheumatic diseases, and have demonstrated therapeutic potency, comparable with other ...
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Clinical efficacy of olmesartan medoxomil
Journal of Hypertension, 2003Olmesartan medoxomil is a new angiotensin-II receptor antagonist for the treatment of hypertension. Olmesartan medoxomil is a pro-drug that is de-esterified to the active metabolite, olmesartan. Olmesartan has a dual method of elimination, with about 60% eliminated by the liver and the remainder by the kidney. In situations of impaired renal or hepatic
Brunner HR, Laeis P
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Clinical Study on the Efficacy of Tonsilloadenoidectomy
Acta Oto-Laryngologica, 1988Controversies regarding the efficacy and indications for tonsilloadenoidectomy have existed for some time. The authors attempt to present an outline in the management of patients with tonsillar and adenoid diseases by carrying out a clinical survey on 1,566 patients who had tonsilloadenoidectomy at the Department of Otolaryngology, Seoul National ...
J Y, Kim, C H, Lee
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Clinical Efficacies of Antihypertensive Drugs
Scandinavian Cardiovascular Journal, 2003According to published data, the ability to prevent various hypertension-related events differs between the various antihypertensive drug groups. Although absolute drug effects differ among studies, relative drug effects could be considered constant. We therefore explored the possibility of drawing statistically valid conclusions about the differences ...
Ivar, Aursnes +3 more
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