Results 91 to 100 of about 575,974 (287)

Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland [PDF]

open access: yes, 2011
The melanocortin-2-receptor (MC2R)/MC2R accessory protein (MRAP) complex is critical to the production of glucocorticoids from the adrenal cortex. Inactivating mutations in either MC2R or MRAP result in the clinical condition familial glucocorticoid ...
Chan, LF   +4 more
core   +2 more sources

Self‐Trapped Excitons in Carbon Quantum Dots with Large NIR‐II Photo‐Thermoelectric Catalysis Induce Pyroptosis for Cancer Therapy

open access: yesAdvanced Science, EarlyView.
The self‐trapped excitons in carbon quantum dots can serve as NIR‐II absorbers, which efficiently induce pyroptosis by driving the generation of reactive oxygen species through mild NIR‐II photothermal effect. Combined with local photophysical therapy and the cascade reaction of pyroptosis, it can activate systemic immunity and prevent tumor recurrence.
Tesen Zhang   +10 more
wiley   +1 more source

Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats [PDF]

open access: yes, 2012
We investigated the effects of different windows of testosterone propionate (TP) treatment during foetal and neonatal life in female rats to determine whether and when excess androgen exposure would cause disruption of adult reproductive function ...
Abbott   +50 more
core   +3 more sources

Identifying Key Questions and Challenges in Microchimerism Biology

open access: yesAdvanced Science, EarlyView.
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua   +31 more
wiley   +1 more source

Letter to the editor of clinical endocrinology: Assessment of adrenal function in patients who survive COVID-19. [PDF]

open access: yesClin Endocrinol (Oxf), 2023
Clarke SA   +12 more
europepmc   +1 more source

Label‐Free Leukocyte Biophysical Profiling Using Impedance‐Deformability Cytometry for Rapid Cardiovascular Risk Stratification

open access: yesAdvanced Science, EarlyView.
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He   +13 more
wiley   +1 more source

THBS1 identificated as an endometriosis biomarker through evidence from single-cell and bulk transcriptomic profiling

open access: yesiScience
Summary: Endometriosis affects a substantial number of women of reproductive age, yet current diagnostic methods rely on invasive procedures. To address this limitation, we investigated THBS1 as a potential biomarker and regulator of disease progression.
Liqi Zhang   +6 more
doaj   +1 more source

Community health orientation of Indian Journal of Endocrinology and Metabolism: A bibliometric analysis of Indian Journal of Endocrinology and Metabolism

open access: yesIndian Journal of Endocrinology and Metabolism, 2015
Background: Endocrine and metabolic diseases especially diabetes have become focus areas for public health professionals. Indian Journal of Endocrinology and Metabolism (IJEM), a publication of Endocrine Society of India, is a peer-reviewed online ...
Kanica Kaushal, Sanjay Kalra
doaj   +1 more source

American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update. [PDF]

open access: yesEndocr Pract, 2022
Blonde L   +28 more
europepmc   +1 more source

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