Results 51 to 60 of about 9,396,953 (279)

European Society of Endocrinology Clinical Practice Guidelines on the Management of Adrenocortical Carcinoma in Adults, in collaboration with the European Network for the Study of Adrenal Tumors.

European Journal of Endocrinology, 2018
Adrenocortical carcinoma (ACC) is a rare and in most cases steroid hormone producing tumor with variable prognosis. The purpose of these guidelines is to provide clinicians with best possible evidence-based recommendations for clinical management of ...
M. Fassnacht, O. Dekkers, T. Else, E. Baudin, A. Berruti, R. D. de Krijger, H. Haak, R. Mihai, G. Assié, M. Terzolo   +9 more
semanticscholar   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Ovarian reserve and anti-Mullerian hormone (AMH) in mothers of dizygotic twins [PDF]

, 2013
This study aimed to explore if natural dizygotic (DZ) twinning is associated with earlier menopause and lower anti-Mullerian hormone (AMH) values. We investigated if advanced biological reproductive aging, which can be responsible for the multiple ...
Boomsma, Dorret I, Konig, Tamar E, Lambalk, Cornelis, Van der Stroom, Elizabeth MC, Vink, Jacqueline M   +4 more
core   +9 more sources

Grid infrastructures supporting paediatric endocrinology across Europe [PDF]

, 2007
Paediatric endocrinology is a highly specialised area of clinical medicine with many experts with specific knowledge distributed over a wide geographical area.
Ajayi, O., Sinnott, R.O., Stell, A.J.
core   +2 more sources

Cardiovascular features of possible autonomous cortisol secretion in patients with adrenal incidentalomas [PDF]

, 2018
Background: Low-grade incomplete post-dexamethasone cortisol suppression in patients with adrenal incidentalomas – recently defined as possible autonomous cortisol secretion (pACS) – has been associated with increased cardiovascular events and mortality.
Di Giorgio, Maria Rosaria, D’Aluisio, Denise, Giannetta, Elisa, Isidori, Andrea M., Lenzi, Andrea, Minnetti, Marianna, Morelli, Sergio, Pofi, Riccardo, Rizza, Laura, Sbardella, Emilia, Venneri, Mary Anna, Vestri, Annarita, Vinci, Fabio   +12 more
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Circulating biomarkers of kidney angiomyolipoma and cysts in tuberous sclerosis complex patients

iScience
Summary: Patients with tuberous sclerosis complex (TSC) develop multi-organ disease manifestations, with kidney angiomyolipomas (AML) and cysts being one of the most common and deadly.
Varvara I. Rubtsova, Yujin Chun, Joohwan Kim, Cuauhtemoc B. Ramirez, Sunhee Jung, Wonsuk Choi, Miranda E. Kelly, Miranda L. Lopez, Elizabeth Cassidy, Gabrielle Rushing, Dean J. Aguiar, Wei Ling Lau, Rebecca S. Ahdoot, Moyra Smith, Aimee L. Edinger, Sang-Guk Lee, Cholsoon Jang, Gina Lee   +17 more
doaj   +1 more source

Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency [PDF]

, 2010
Objective: Patients with congenital adrenal hyperplasia due to P450 oxidoreductase (POR) deficiency(ORD) present with disordered sex development and glucocorticoid deficiency.
Arlt, Bebia, Chang, de Morais, Dominique Maiter, Dorota Tomalik-Scharte, Fl  ck, Fuhr, Gomes, Hannah E Ivison, Henderson, Jetter, Julia Kirchheiner, Kelley, Kirchheiner, Kranendonk, Nebert, Nicolo, Parkinson, Porter, Ribes, Sachse, Tantcheva-Po  r, Tomalik-Scharte, Uwe Fuhr, Wiebke Arlt   +25 more
core   +2 more sources

Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman, David G. Stouffer, Dae‐Gyu Jang, Jihyun Park, Benjamin J. Murdock, Richard J. Auchus   +5 more
wiley   +1 more source

Primary hyperparathyroidism clinical features on endocrinology in-patients clinic

Терапевтический архив, 2018
Aim. The analysis clinical features of primary hyperparathyroidism on endocrinology in-patients clinic. Materials and methods. Open retrospective study, included data of patients who were hospitalized at Kirov Regional Hospital with primary ...
I E Sapozhnikova
doaj   +1 more source