Results 51 to 60 of about 575,974 (287)

Primary hyperparathyroidism clinical features on endocrinology in-patients clinic

open access: yesТерапевтический архив, 2018
Aim. The analysis clinical features of primary hyperparathyroidism on endocrinology in-patients clinic. Materials and methods. Open retrospective study, included data of patients who were hospitalized at Kirov Regional Hospital with primary ...
I E Sapozhnikova
doaj   +1 more source

CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target

open access: yesAdvanced Science, EarlyView.
CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo   +15 more
wiley   +1 more source

Management of Glucocorticoid-Induced Hyperglycemia

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2022
Parag Shah,1 Sanjay Kalra,2 Yogesh Yadav,3 Nilakshi Deka,4 Tejal Lathia,5 Jubbin Jagan Jacob,6 Sunil Kumar Kota,7 Saptrishi Bhattacharya,8 Sharvil S Gadve,9 KAV Subramanium,10 Joe George,11 Vageesh Iyer,12 Sujit Chandratreya,13 Pankaj Kumar Aggrawal,14 ...
Shah P   +19 more
doaj  

The pituitary TGFb1 system as a novel target for the treatment of resistant prolactinomas [PDF]

open access: yes, 2016
Prolactinomas are the most frequently observed pituitary adenomas and most of themrespond well to conventional treatment with dopamine agonists (DAs).
Camilletti, María Andrea   +3 more
core   +2 more sources

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

open access: yesAdvanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma   +11 more
wiley   +1 more source

Request of endocrinology and metabolism journals for data sharing statements in clinical trial reports: a survey

open access: yesFrontiers in Medicine
BackgroundTo enhance reproducibility and transparency, the International Committee of Medical Journal Editors (ICMJE) required that all trial reports submitted after July 2018 must include a data sharing statement (DSS).
Yingxin Liu   +8 more
doaj   +1 more source

The making of an endocrinologist in India: Life and times at Institute of Post Graduate Medical Education and Research Calcutta

open access: yesIndian Journal of Endocrinology and Metabolism, 2015
Endocrinology is relatively one of the newer super-specialties of internal medicine. Following higher secondary schooling, it takes anywhere between 13 and 18 years to become a super-specialist in India, which holds true for endocrinology also.
Deep Dutta
doaj   +1 more source

Application of social hotspots on case-based teaching method during the teaching of endocrinology [PDF]

open access: yesJichu yixue yu linchuang, 2021
In order to improve the quality of clinical endocrinology courses, social hotspots penetrated into professional instructions of endocrinology and well tailored with curriculum knowledge.
FANG Hong-juan, ZHONG Li-yong
doaj  

A systematic review of patient-reported outcome measures in paediatric endocrinology

open access: yesBMC Endocrine Disorders, 2022
Context Patient reported outcome measures (PROMs) are useful tools in paediatric endocrinology to gauge health status in children, especially since they are often unable to clearly communicate it themselves. We aimed to systematically search and appraise
Richard G. McGee   +4 more
doaj   +1 more source

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

open access: yesAdvanced Science, EarlyView.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun   +16 more
wiley   +1 more source

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