Results 51 to 60 of about 5,693,843 (277)

eEF1G Orchestrates Translation to Ensure Meiotic Progression in Transcriptionally Quiescent Spermatocytes

open access: yesAdvanced Science, EarlyView.
eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu   +12 more
wiley   +1 more source

Request of endocrinology and metabolism journals for data sharing statements in clinical trial reports: a survey

open access: yesFrontiers in Medicine
BackgroundTo enhance reproducibility and transparency, the International Committee of Medical Journal Editors (ICMJE) required that all trial reports submitted after July 2018 must include a data sharing statement (DSS).
Yingxin Liu   +8 more
doaj   +1 more source

The making of an endocrinologist in India: Life and times at Institute of Post Graduate Medical Education and Research Calcutta

open access: yesIndian Journal of Endocrinology and Metabolism, 2015
Endocrinology is relatively one of the newer super-specialties of internal medicine. Following higher secondary schooling, it takes anywhere between 13 and 18 years to become a super-specialist in India, which holds true for endocrinology also.
Deep Dutta
doaj   +1 more source

Clinical Reproductive Endocrinology

open access: yes, 2008
This chapter helps in understating the basics of clinical reproductive endocrinology. Clinical reproductive endocrinology includes the study of diseases and secretory status of the endocrine glands involved in reproduction and their secretory products ...
Andersson, Håkan,, Håkan Andersson
core   +1 more source

Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population‐Based Study and Gut Microbiota Analysis

open access: yesAdvanced Science, EarlyView.
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi   +14 more
wiley   +1 more source

European Society of Endocrinology Clinical Practice Guidelines for the management of aggressive pituitary tumours and carcinomas

open access: yes, 2018
BACKGROUND: Pituitary tumours are common and easily treated by surgery or medical treatment in most cases. However, a small subset of pituitary tumours does not respond to standard medical treatment and presents with multiple local recurrences ...
Heaney, A.   +34 more
core   +1 more source

8‐Oxoguanine Modified CircMTUS1 Drives PABPC1 Phase Separation to Promote Gastric Cancer Progression and Cisplatin Resistance via Autophagy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gastric cancer (GC) is a major global health concern, as its prevention and treatment remain significant challenges. The 8‐oxoguanine (o8G) modification of circRNAs, alongside their capacity to orchestrate liquid‐liquid phase separation (LLPS) and autophagy, plays a pivotal role in driving tumor progression and determining therapeutic outcomes.
Lei Peng   +8 more
wiley   +1 more source

Application of social hotspots on case-based teaching method during the teaching of endocrinology [PDF]

open access: yesJichu yixue yu linchuang, 2021
In order to improve the quality of clinical endocrinology courses, social hotspots penetrated into professional instructions of endocrinology and well tailored with curriculum knowledge.
FANG Hong-juan, ZHONG Li-yong
doaj  

A systematic review of patient-reported outcome measures in paediatric endocrinology

open access: yesBMC Endocrine Disorders, 2022
Context Patient reported outcome measures (PROMs) are useful tools in paediatric endocrinology to gauge health status in children, especially since they are often unable to clearly communicate it themselves. We aimed to systematically search and appraise
Richard G. McGee   +4 more
doaj   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

open access: yesAdvanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song   +5 more
wiley   +1 more source

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