Results 201 to 210 of about 2,660,626 (386)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Brazilian consensus- and evidence-based recommendations in the diagnosis and treatment of pancreatic exocrine insufficiency in patients after digestive surgeries. Position paper of six brazilian medical societies of surgery. [PDF]

Arq Bras Cir Dig
Montagnini AL, Bernardo WM, Kassab P, Quireze Junior C, Oliveira CVC, Diniz AL, Pinheiro RN, Oliveira AF, Portari Filho P, Ravanini GAG, Forones NM, Pertille MFK, Valezi AC, Dantas ACB, Marzinotto MAN, Figueira ER, Jukemura J, Ribeiro Junior U, Herman P.   +18 more
europepmc   +1 more source

Clinical and metabolic correction of pompe disease by enzyme therapy in acid maltase-deficient quail.

Journal of Clinical Investigation, 1998
Tateki Kikuchi, Helen W. Yang, Mark Pennybacker, Nobutsune Ichihara, Makoto Mizutani, J. L. Hove, Yuan-Tsong Chen   +6 more
semanticscholar   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Simvastatin combined with antiviral therapy for hepatitis B cirrhosis with portal hypertension: A case report. [PDF]

Medicine (Baltimore)
Zhang H, Li J, Zhou Y, Li X, Wang H, Gou W, Liu Z, Qi X.   +7 more
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Paraneoplastic Pemphigus Mimicking Pemphigus Herpetiformis - Overlap of Two Diseases. [PDF]

Acta Derm Venereol
Maeda S, Tsutsumi M, Teye K, Ishii N, Koga H.   +4 more
europepmc   +1 more source

Assessment of enzyme detection tests useful in identification of campylobacteria

Journal of Clinical Microbiology, 1992
S. On, B. Holmes
semanticscholar   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Defining 'Normal' Liver Function Tests. [PDF]

Cureus
Chong P, Gnanendran D, Gao-Du YX, Millson C.   +3 more
europepmc   +1 more source