Results 131 to 140 of about 2,180,698 (310)

Interprofessional education in clinical ethics

GMS Zeitschrift für Medizinische Ausbildung, 2005
Interprofessional ethics education means: a) teaching together students from those professions, that in future will be working together on the ward, and b) teaching them patient-centred, shared clinical decision-making.
Neitzke, Gerald
doaj  

Clinical ethics consultation documentation in the era of open notes. [PDF]

BMC Med Ethics, 2023
Childers C, Marron J, Meyer EC, Abel GA.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Bedside Teaching and Respecting the Pediatric Patient

BioéthiqueOnline, 2015
Bedside teaching involving patients, physicians, and students is a ubiquitous technique used for medical training. Respect, valid informed consent, and transparency are key to ethical and effective teaching.
Touyz, Sarah Judith Jean
doaj  

Clinical Ethics Committee in an Oncological Research Hospital: two-years Report. [PDF]

Nurs Ethics, 2023
Perin M, De Panfilis L, Clinical Ethics Committee of the Azienda USL-IRCCS di Reggio Emilia.   +2 more
europepmc   +1 more source

Professional Ethics of Medical Interns in Clinical Settings of Mazandaran University of Medical Sciences from the Perspective of Professors: A Descriptive-Analytical Study

, 2021
Abdolmajid Gholinataj, Ali Ravanbod, Masoumeh Bagheri‐Nesami, Zahra Mardanshahi   +3 more
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Compte-rendu de L’éthique clinique : pour une approche relationnelle dans les soins, 2014, Hubert Doucet, Paramètres, Les Presses de l’Université de Montréal

BioéthiqueOnline, 2017
In his book L’éthique clinique pour une approche relationnelle (Clinical Ethics: A Relational Approach), Hubert Doucet proposes an approach to clinical ethics that includes various theoretical and practical perspectives, notably that of the philosopher ...
Roigt, Delphine
doaj  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source