Results 151 to 160 of about 2,180,698 (310)

Developing Organizational Diversity Statements Through Dialogical Clinical Ethics Support: The Role of the Clinical Ethicist. [PDF]

J Bioeth Inq, 2023
Kröger C, Molewijk AC, Metselaar S.
europepmc   +1 more source

Developing a ‘moral compass tool’ based on moral case deliberations: A pragmatic hermeneutic approach to clinical ethics [PDF]

, 2019
Laura Hartman, Suzanne Metselaar, Guy Widdershoven, Bert Molewijk   +3 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Correction: How to deal with the criterion of severe mental distress for late termination of pregnancy? A scoping literature review and a content analysis of clinical ethics consultations. [PDF]

BMC Med Ethics
Wetterauer C, Schürmann J, Winkler L, Westermair AL, Biller-Andorno N, Tschudin S, Manegold-Brauer G, Trachsel M.   +7 more
europepmc   +1 more source

Engaging Tomorrow's Doctors in Clinical Ethics: Implications for Healthcare Organisations. [PDF]

Health Care Anal, 2021
Machin LL, Proctor RD.
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

CURA: A clinical ethics support instrument for caregivers in palliative care. [PDF]

Nurs Ethics, 2022
Metselaar S, van Schaik M, Widdershoven G, Pasman HR.   +3 more
europepmc   +1 more source

Ethics: The Bedrock of Research and Clinical Practice

, 2009
Joseph G. McVeigh
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Ethics support personnel's perceptions of patient and parent participation in clinical ethics support services in pediatric oncology. [PDF]

BMC Med Ethics
Billstein I, Bartholdson C, Castor A, Molewijk B, Pergert P.   +4 more
europepmc   +1 more source