Results 21 to 30 of about 21,937,235 (349)
The upper and lower respiratory tract microbiome in severe aspiration pneumonia
iScience, 2023 Summary: Uncertainty persists whether anaerobic bacteria represent important pathogens in aspiration pneumonia. In a nested case-control study of mechanically ventilated patients classified as macro-aspiration pneumonia (MAsP, n = 56), non-macro ...
Georgios D. Kitsios +22 more
doaj +1 more source
Optimal designs for active controlled dose finding trials with efficacy-toxicity outcomes [PDF]
, 2016 Nonlinear regression models addressing both efficacy and toxicity outcomes are increasingly used in dose-finding trials, such as in pharmaceutical drug development.
Bretz, Frank +4 more
core +3 more sources
Racial heterogeneity of IgA1 hinge-region O-glycoforms in patients with IgA nephropathy
iScience, 2022 Summary: Galactose (Gal)-deficient IgA1 (Gd-IgA1) is involved in IgA nephropathy (IgAN) pathogenesis. To reflect racial differences in clinical characteristics, we assessed disease- and race-specific heterogeneity in the O-glycosylation of the IgA1 hinge
Yukako Ohyama +17 more
doaj +1 more source
Lymphoma and hypercalcemia in a pediatric orthotopic liver transplant patient [PDF]
, 1989 We present a case report of a pediatric orthotopic liver transplant recipient who developed lymphoma with hypercalcemia on cyclosporine and prednisone immunosuppression.
Esquivel, CO +6 more
core +1 more source
iScience, 2023 Summary: Aberrant minichromosome maintenance (MCM) expression is associated with tumorigenesis. Here, we performed immunohistochemistry integrated with digital pathology to identify MCM2/5/6 expression in 130 neuroblastoma patients.
Liang Zeng +9 more
doaj +1 more source
The C9ORF72 mutation brings more answers and more questions. [PDF]
, 2013 The clinical, neuropsychiatric and neuroimaging features of patients who carry the important new C9ORF72 mutation are discussed in this special series of Alzheimer's Research & Therapy.
Miller, Bruce L
core +1 more source
Interpretable deep learning for automatic diagnosis of 12-lead electrocardiogram
iScience, 2021 Summary: Electrocardiogram (ECG) is a widely used reliable, non-invasive approach for cardiovascular disease diagnosis. With the rapid growth of ECG examinations and the insufficiency of cardiologists, accurate and automatic diagnosis of ECG signals has ...
Dongdong Zhang +3 more
doaj +1 more source
Neural correlates of outcome of the psychotherapy compared to antidepressant therapy in anxiety and depression disorders: a meta-analysis [PDF]
, 2017 The most prevalent mental disorders, anxiety and depression, are commonly associated with structural and functional changes in the fronto-limbic brain areas.
Aceto, Paola +6 more
core +3 more sources
Profiling of exhaled volatile organics in the screening scenario of a COVID-19 test center
iScience, 2022 Summary: Breath volatile organics (VOCs) may provide immediate information on infection mechanisms and host response. We conducted real-time mass spectrometry-based breath profiling in 708 non-preselected consecutive subjects in the screening scenario of
Rasmus Remy +9 more
doaj +1 more source
iScience, 2022 Summary: Different immune-mediated diseases have been described after SARS-CoV-2 vaccination, with antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) being one of the possible side effects.
Juan Irure-Ventura +8 more
doaj +1 more source