Results 191 to 200 of about 1,217,808 (321)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Integrating genetics into medical curriculum: evaluating a dedicated clinical genetics module at Dow university of health sciences. [PDF]

BMC Med Educ
Hanif MI, Bari MF, Hussain M, Khan N, Hossain N, Quraishy MS, Kirmani S.   +6 more
europepmc   +1 more source

Novel Findings into AIRE Genetics and Functioning: Clinical Implications [PDF]

, 2016
Lucia De Martino, Donatella Capalbo, Nicola Improda, Paola Lorello, Carla Ungaro, Raffaella Di Mase, Emilia Cirillo, Claudio Pignata, Mariacarolina Salerno   +8 more
openalex   +1 more source

Data from Gender Disparities in the Tumor Genetics and Clinical Outcome of Multiple Myeloma

, 2023
Kevin Boyd, Fiona M. Ross, Laura Chiecchio, Gian Paolo Dagrada, Zoë J. Konn, William Tapper, Brian A. Walker, Christopher P. Wardell, Walter M. Gregory, Alex J. Szubert, Faith E. Davies, Gareth J. Morgan   +11 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Patient care practices for LGBTQ+ individuals in clinical genetics: A scoping review. [PDF]

J Genet Couns
Zayhowski K, Horowitz K, Bostrom M, Mittendorf KF, Kocher M, Austin JJ, MacFarlane IM.   +6 more
europepmc   +1 more source

Scope of professional roles for genetic counsellors and clinical geneticists in the United Kingdom : Position on behalf of the Association of Genetic Nurses and Counsellors and the Clinical Genetics Society. [PDF]

Eur J Hum Genet, 2023
Middleton A, Taverner N, Houghton C, Smithson S, Balasubramanian M, Elmslie F.   +5 more
europepmc   +1 more source

Molecular technology vs clinical practice: a hypothesis in genetics [PDF]

, 2010
Haris Kokotas
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Current landscape of clinical genetics knowledge and attitudes among Non-Geneticist Physicians - the McGill genetics education survey (McGES). [PDF]

J Community Genet
Abdullah-Maklan S, Trakadis Y.
europepmc   +1 more source