Results 241 to 250 of about 591,252 (334)

Molecular genetics of CYP2D6: Clinical relevance with focus on psychotropic drugs [PDF]

, 2002
Leif Bertilsson, Marja­‐Liisa Dahl, Per Dalén, Ayman Al‐Shurbaji   +3 more
openalex   +1 more source

Pediatric Clinical Genetics

, 2016
Andrew J. Green, James J. O’Byrne
openaire   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Patterns of referrals to regional clinical genetics services for women potentially at above-population level risk of breast cancer. [PDF]

BJC Rep
Usher-Smith JA, Tooth G, Follows A, Badran AR, Youngs A, Forman A, Snape K, Antoniou AC, Tischkowitz M.   +8 more
europepmc   +1 more source

Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management

, 2001
Tim C. P. Somervaille
openalex   +1 more source

Integration of genetics into clinical teaching in medical school education [PDF]

, 2002
Bruce R. Korf
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Continuous medical education approaches for clinical genetics: a postal survey of general practitioners [PDF]

, 2002
Nadeem Qureshi
openalex   +1 more source

The development of clinical genetics. [PDF]

Journal of Medical Genetics, 1981
openaire   +3 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source