Results 251 to 260 of about 591,252 (334)
Clinical Genetics of Prolidase Deficiency: An Updated Review. [PDF]
Biology (Basel), 2020 Spodenkiewicz M +9 more
europepmc +1 more source
Clinical genetics in cancer prevention
Hereditary Cancer in Clinical Practice, 2012 Elsakov Pavel
doaj +1 more source
Molecular Oncology, EarlyView.Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger +2 more
wiley +1 more source
The impact of molecular genetics on the clinical management of pediatric sensorineural hearing loss [PDF]
, 2002 Daniel Choo
openalex +1 more source
Genetics and clinical enzymology. [PDF]
Journal of Clinical Pathology, 1970 openaire +2 more sources
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
Growth in perceived clinical genetics competency among primary care providers participating in genomic population health screening. [PDF]
J Community GenetHansen CA, Reiter AW, Wildin RS.
europepmc +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source