Results 261 to 270 of about 1,217,808 (321)

[The genetics of obesity - pathogenetic, clinical and diagnostic aspects].

, 2019
A. Barczyk, Anna Kutkowska‐Kaźmierczak, Jennifer Castañeda, Ewa Obersztyn   +3 more
openalex   +2 more sources

Molecular genetics of common variable immunodeficiency

, 2017
Bogaert, Delfien, De Baere, Elfride, Dullaers, Melissa, Haerynck, Filomeen   +3 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Management of individuals with heterozygous germline pathogenic variants in RAD51C, RAD51D, and BRIP1: A clinical practice resource of the American College of Medical Genetics and Genomics (ACMG).

Joanne Ngeow, Jianbang Chiang, Esteban Astiazarán-Symonds, Judith Balmaña, Ilana Cass, Felix KF Kommoss, William D Foulkes, Paul A James, Arielle Katcher, Susan Klugman, Alicia A. Livinski, Julie S Mak, Nicoleta Voian, Myra Wick, Marc Tischkowitz, Tuya Pal, Douglas R. Stewart, Helen Hanson, ACMG Professional Practice and Guidelines Committee. Electronic address: documents@acmg.net   +18 more
openalex   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Growth in perceived clinical genetics competency among primary care providers participating in genomic population health screening. [PDF]

J Community Genet
Hansen CA, Reiter AW, Wildin RS.
europepmc   +1 more source

Psychological Treatment of a BRCA gene mutation carrier in a Clinical Genetics Service using Solution Focused Therapy (SFT): – A Case Study

, 2022
Firth C, Tripathi V.
europepmc   +1 more source

Clinical variants of acrodermatitis enteropathica and its co-relation with genetics

, 2016
Sarabjit Kaur, Ankita Sangwan, Priyadarshini Sahu, Surabhi Dayal, VijayKumar Jain   +4 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

A recurrent mosaic mutation in SMO, encoding the hedgehog signal transducer smoothened, is the major cause of Curry-Jones syndrome [PDF]

, 2016
et al,, Grange, Dorothy K
core   +1 more source