Results 221 to 230 of about 5,855,669 (305)

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guideline for Diagnosing and Managing Acute Coronary Syndromes 2025. [PDF]

Med J Aust
Brieger DB, Cullen LA, Briffa TG, Zaman S, Scott IA, Papendick C, Ho E, Leitch V, Dougherty D, Jennings G.   +9 more
europepmc   +1 more source

Clinical Practice Guidelines

Indian Journal of Psychiatry, 2017
openaire   +2 more sources

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Diabetes management using a clinical guideline versus usual practice: a feasibility trial-based qualitative study among Ayurvedic practitioners and patients in Nepal. [PDF]

Ther Adv Endocrinol Metab
Chattopadhyay K, Rana N, Karki S, Regmi P, Gyanwali P, Upadhyay V, Bista B, Tandon N, Kinra S, Biswas TK, Leonardi-Bee J, Heinrich M, Panniyammakal J, Lewis SA, Greenfield SM, Dhimal M.   +15 more
europepmc   +1 more source

A Novel KCNA1 Variant in a Patient With Tremor and Autism Spectrum Disorder Causes Mixed LOF/GOF Defects of Kv1.1 Channels

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Variants in KCNA1, encoding the Kv1.1 potassium channel, cause neurological disorders including episodic ataxia and developmental and epileptic encephalopathy. We identified a novel KCNA1 variant (A401T) in a 16‐year‐old patient with autism spectrum disorder, borderline intellectual disability, and tremor, without episodic ataxia or epilepsy ...
Juan Darío Ortigoza‐Escobar, Laura Marti‐Sánchez, Loreto Martorell, Giorgia Dinoi, Antonio Vittorio Buono, Annamaria De Luca, Antonella Liantonio, Paola Imbrici   +7 more
wiley   +1 more source

Diabetes Management by Ayurvedic Practitioners Using a Clinical Guideline Versus Usual Practice: A Feasibility Cluster Randomized Trial in Nepal. [PDF]

J Diabetes Res
Chattopadhyay K, Karki S, Wang H, Regmi P, Gyanwali P, Upadhyay V, Heinrich M, Bista B, Tandon N, Kinra S, Greenfield SM, Biswas TK, Jeemon P, Leonardi-Bee J, Lewis SA, Dhimal M.   +15 more
europepmc   +1 more source

Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity

Arthritis Care &Research, EarlyView.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source

Z-drug abuse and dependence: clinical guideline of the Brazilian Academy of Neurology for diagnosis and management. [PDF]

Arq Neuropsiquiatr
Stelzer FG, Bacelar A, Éckeli AL, Negrão AB, Almeida CMO, Franco CMR, Pires GN, Gitaí LLG, Sobreira-Neto MA, Assis M, Mei PA, Hasan R, Martinez SCG, Marchiori T, Fidalgo TM, Siqueira LL, Poyares D.   +16 more
europepmc   +1 more source

Clinical Guideline for Detection and Management of Magnesium Deficiency in Ambulatory Care. [PDF]

Nutrients
Colaneri-Day S, Rosanoff A.
europepmc   +1 more source