Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Clinical history and incidental abnormality detection in endodontic cone beam computed tomography. [PDF]
J Med Imaging (Bellingham), 2023 Yapp KE, Ekpo E.
europepmc +1 more source
The Importance Of The Clinical History and Oral Challenge Against Misleading False-positive Supplementary Tests In The Study Of Drug Allergies. [PDF]
, 2020 Ricardo Moreno-Borque +2 more
openalex +1 more source
The use of pure carbon for permanent percutaneous electrical connector systems [PDF]
Pure carbon was used as an electrode in the clinical application of long-term neuromuscular stimulation, as well as a connector for permanent neuroelectrodes.
Benson, J. +3 more
core +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Association between clinical history in the radiographic request and diagnostic accuracy of thorax radiographs in dogs: A retrospective case-control study. [PDF]
J Vet Intern Med, 2023 Arruda Bergamaschi N +8 more
europepmc +1 more source
Bias in the Reporting of Family History: Implications for Clinical Care [PDF]
, 2012 Elissa M. Ozanne +11 more
openalex +1 more source