Results 201 to 210 of about 4,346,835 (341)

Optimizing Electrodiagnostic Studies: The Role of Clinical History in Improving Diagnostic Concordance-A Retrospective Study. [PDF]

open access: yesDiagnostics (Basel)
López-López CO   +3 more
europepmc   +1 more source

Validation of a newly developed questionnaire regarding clinical history in patients with breast and colorectal cancers. [PDF]

open access: yesARYA Atheroscler, 2021
Vafaei Z   +11 more
europepmc   +1 more source

13. Developing a Brief Clinical Pathway for Trauma-Focused Management of Individuals With Trauma Histories Admitted to the Medical Hospital

open access: hybrid
Sophia Buzanis   +6 more
openalex   +1 more source

Natural History of Nipah Virus in Hamsters: Strain, Route, and Sex-Associated Variability Characterized Using Large Datasets to Inform Pre-Clinical Study Design [PDF]

open access: hybrid
Katherine Davies   +6 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

A case of a (not so) diffuse leptomeningeal glioneuronal tumor with an unusual clinical history. [PDF]

open access: yesJ Neuropathol Exp Neurol
Faraj CA   +6 more
europepmc   +1 more source

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