Results 231 to 240 of about 4,346,835 (341)

Does a history of sickle cell disease affect the prescription of morphine? An international, randomised study based on clinical vignettes conducted among emergency physicians [PDF]

Fabien Coisy, Alexandre Simon, Céline Occelli, Florence Dupriez, François‐Xavier Ageron, Lorie N’Diaye, Anne‐Laure Féral‐Pierssens, Gregory Yates, Xavier Bobbia   +8 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Risk Assessment for Preeclampsia in the Preconception Period Based on Maternal Clinical History via Machine Learning Methods. [PDF]

J Clin Med
Kaya Y, Bütün Z, Çelik Ö, Salik EA, Tahta T.   +4 more
europepmc   +1 more source

Left Ventricular Assist Devices (LVADS): History, Clinical Application and Complications [PDF]

, 2019
Howard J. Eisen
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Clinical history correlates with lateral atlantoaxial (C1-2) joint edema. A pilot study. [PDF]

Interv Pain Med
Levin J, Kaufman M, Yeung G.
europepmc   +1 more source

Observable phenomena that reveal medical students' clinical reasoning ability during expert assessment of their history taking: a qualitative study [PDF]

, 2017
Catharina Maria Haring, Bernadette Cools, Petra J. van Gurp, J.W.M. van der Meer, Cornelis T. Postma   +4 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

HPV DNA status and clinical history of patients are supplements for accurate reporting of the cytological Pap smear. [PDF]

Sci Rep
Ali M, Sinha R, Kumar A, Karim S, Irfan M, Kumar S, Sinha S, Kumar A, Ghosh A, Singh M.   +9 more
europepmc   +1 more source

Leptomeningeal dissemination of anaplastic medullary cone astrocytoma: an unexpected findings in a patient with leptomeningeal enhancement and clinical history of multiple myeloma. [PDF]

Pathologica, 2021
Daffini L, Pagani F, Cominelli M, Lodoli G, Tironi A, Poliani PL.   +5 more
europepmc   +1 more source