Results 11 to 20 of about 29,665,310 (345)

COVIDrugNet: a network-based web tool to investigate the drugs currently in clinical trial to contrast COVID-19

Scientific Reports, 2021
The COVID-19 pandemic poses a huge problem of public health that requires the implementation of all available means to contrast it, and drugs are one of them.
Luca Menestrina, Chiara Cabrelle, Maurizio Recanatini   +2 more
doaj   +1 more source

A novel defined m7G regulator signature to investigate the association between molecular characterization and clinical significance in lung adenocarcinoma

Frontiers in Oncology, 2022
BackgroundAbout170 chemical modifications to RNAs have been identified, which significantly affect gene expression. Dysregulation of RNA modifications induced by abnormal expression or mutations in RNA modifiers might result in cancer.
Yi Dong, Yingge Li, Yi Yao, Qibin Song
doaj   +1 more source

Bayesian P-Splines to investigate the impact of covariates on Multiple Sclerosis clinical course [PDF]

, 2003
This paper aims at proposing suitable statistical tools to address heterogeneity in repeated measures, within a Multiple Sclerosis (MS) longitudinal study.
Di Serio, C., Lamina, C.
core   +1 more source

A systematic review of clinical decision support systems for antimicrobial management: are we failing to investigate these interventions appropriately?

Clinical Microbiology and Infection, 2017
OBJECTIVES Clinical decision support systems (CDSS) for antimicrobial management can support clinicians to optimize antimicrobial therapy. We reviewed all original literature (qualitative and quantitative) to understand the current scope of CDSS for ...
T. Rawson, Luke S.P. Moore, Bernard Hernandez, E. Charani, E. Castro-Sánchez, P. Herrero, B. Hayhoe, W. Hope, P. Georgiou, A. Holmes   +9 more
semanticscholar   +1 more source

Prevalence of asthma and COPD and blood eosinophil count in a middle-aged Belgian population [PDF]

, 2019
Various phenotypes exist in asthma and Chronic Obstructive Pulmonary Disease (COPD). These are important to identify in order to guide treatment decisions.
Brusselle, Guy, De Buyzere, Marc, Lahousse, Lies, Rietzschel, Ernst, Wijnant, Sara   +4 more
core   +1 more source

New Approaches in Breast Cancer Therapy Through Green Nanotechnology and Nano-Ayurvedic Medicine – Pre-Clinical and Pilot Human Clinical Investigations

International Journal of Nanomedicine, 2020
Purpose The overarching objective of this investigation was to investigate the intervention of green nanotechnology to transform the ancient holistic Ayurvedic medicine scientifically credible through reproducible formulations and rigorous pre-clinical ...
M. Khoobchandani, K. Katti, A. R. Karikachery, V. Thipe, D. Srisrimal, DarshaKumar Dhurvas Mohandoss, Rashmi Dhurvas Darshakumar, Chintamani M Joshi, K. Katti   +8 more
semanticscholar   +1 more source

Aberrant functional connectivity within the basal ganglia of patients with Parkinson's disease

NeuroImage: Clinical, 2015
Resting state functional MRI (rs-fMRI) has been previously shown to be a promising tool for the assessment of early Parkinson's disease (PD). In order to assess whether changes within the basal ganglia network (BGN) are disease specific or relate to ...
Michal Rolinski, Ludovica Griffanti, Konrad Szewczyk-Krolikowski, Ricarda A.L. Menke, Gordon K. Wilcock, Nicola Filippini, Giovanna Zamboni, Michele T.M. Hu, Clare E. Mackay   +8 more
doaj   +1 more source

NIHSS Scores in Ischemic Small Vessel Disease: A Study in CADASIL [PDF]

, 2012
Background: The National Institutes of Health Stroke Scale (NIHSS) is widely used to measure neurological deficits, evaluate the effectiveness of treatment and predict outcome in acute ischemic stroke.
Allili, Nassira, Chabriat, Hugues, Dichgans, Martin, Duering, Marco, Herve, Dominique, Jouvent, Eric, Yao, Ming   +6 more
core   +1 more source

Simulated Clinical Encounters Using Patient-Operated mHealth: Experimental Study to Investigate Patient-Provider Communication

JMIR mHealth and uHealth, 2018
BackgroundThis study investigates patient-centered mobile health (mHealth) technology in terms of the secondary user experience (UX). Specifically, it examines how personal mobile technology, under patient control, can be used to improve patient-provider
Tunnell, Harry, Faiola, Anthony, Bolchini, Davide, Bartlett Ellis, Rebecca   +3 more
doaj   +1 more source

The Preservation of Cued Recall in the Acute Mentally Fatigued State: A Randomised Crossover Study. [PDF]

, 2015
The objective of this study is to investigate the impact of acute mental fatigue on the recall of clinical information in the non-sleep-deprived state.
Darzi, A, Flindall, IR, Leff, DR, Pucks, N, Sugden, C   +4 more
core   +2 more sources