Results 11 to 20 of about 2,120,941 (241)

Aberrant functional connectivity within the basal ganglia of patients with Parkinson's disease

NeuroImage: Clinical, 2015
Resting state functional MRI (rs-fMRI) has been previously shown to be a promising tool for the assessment of early Parkinson's disease (PD). In order to assess whether changes within the basal ganglia network (BGN) are disease specific or relate to ...
Michal Rolinski, Ludovica Griffanti, Konrad Szewczyk-Krolikowski, Ricarda A.L. Menke, Gordon K. Wilcock, Nicola Filippini, Giovanna Zamboni, Michele T.M. Hu, Clare E. Mackay   +8 more
doaj   +1 more source

A novel defined m7G regulator signature to investigate the association between molecular characterization and clinical significance in lung adenocarcinoma

Frontiers in Oncology, 2022
BackgroundAbout170 chemical modifications to RNAs have been identified, which significantly affect gene expression. Dysregulation of RNA modifications induced by abnormal expression or mutations in RNA modifiers might result in cancer.
Yi Dong, Yingge Li, Yi Yao, Qibin Song
doaj   +1 more source

Simulated Clinical Encounters Using Patient-Operated mHealth: Experimental Study to Investigate Patient-Provider Communication

JMIR mHealth and uHealth, 2018
BackgroundThis study investigates patient-centered mobile health (mHealth) technology in terms of the secondary user experience (UX). Specifically, it examines how personal mobile technology, under patient control, can be used to improve patient-provider
Tunnell, Harry, Faiola, Anthony, Bolchini, Davide, Bartlett Ellis, Rebecca   +3 more
doaj   +1 more source

Investigator Responsibilities in Clinical Research [PDF]

Ochsner Journal, 2020
Background: Clinical trials are an integral part of translating new basic science research into therapeutics. It is crucial for those who run clinical trials to realize the gravity of their responsibilities as principal investigators. Methods: This review focuses on the relevant investigator responsibilities under the Code of Federal Regulations Title ...
Feehan, Amy K., Garcia-Diaz, Julia
openaire   +5 more sources

Fallers after stroke: a retrospective study to investigate the combination of postural sway measures and clinical information in faller’s identification

Frontiers in Neurology, 2023
BackgroundFalls can have devastating effects on quality of life. No clear relationships have been identified between clinical and stabilometric postural measures and falling in persons after stroke.ObjectiveThis cross-sectional study investigates the ...
Johanna Jonsdottir, Fabiola Giovanna Mestanza Mattos, Alessandro Torchio, Chiara Corrini, Davide Cattaneo, Davide Cattaneo   +5 more
doaj   +1 more source

A Clinical Trial to Investigate the Effect of Cynatine HNS on Hair and Nail Parameters

The Scientific World Journal, 2014
Objective. A new, novel product, Cynatine HNS, was evaluated for its effects as a supplement for improving various aspects of hair and nails in a randomized, double-blind, placebo-controlled clinical trial. Methods.
Christina Beer, Simon Wood, Robert H. Veghte   +2 more
doaj   +1 more source

The clinical significance of incidental intra-abdominal findings on positron emission tomography performed to investigate pulmonary nodules

World Journal of Surgical Oncology, 2012
Background Lung cancer is a common cause of cancer-related death. Staging typically includes positron emission tomography (PET) scanning, in which18F-fluoro-2-dexoy-D-glucose (FDG) is taken up by cells proportional to metabolic activity, thus aiding in ...
Gill Richdeep S, Perry Troy, Abele Jonathan T, Bédard Eric LR, Schiller Daniel   +4 more
doaj   +1 more source

Study protocol designed to investigate tumour response to calcium electroporation in cancers affecting the skin: a non-randomised phase II clinical trial

BMJ Open, 2021
Introduction Skin malignancy is a distressing problem for many patients, and clinical management is challenging. This article describes the protocol for the Calcium Electroporation Response Study (CaEP-R) designed to investigate tumour response to ...
Julie Gehl, Lars Henrik Jensen, Mille Vissing, John Ploen, Mascha Pervan, Kitt Vestergaard, Mazen Schnefeldt, Stine Krog Frandsen, Søren Rafael Rafaelsen, Christina Louise Lindhardt, Achim Rody   +10 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source