Results 281 to 290 of about 29,665,310 (345)
Some of the next articles are maybe not open access.
Canadian Medical Association journal, 2010
Abstract Disease markers are pathological or physiological characteristics of an individual that assist in determining the diagnosis, the current activity of disease, or the expected prognosis of the condition in that individual. Some markers relate to just one of these elements; others may relate to two, or occasionally all three ...
Michael Doherty, Peter C. Lanyon
openaire +3 more sources
Abstract Disease markers are pathological or physiological characteristics of an individual that assist in determining the diagnosis, the current activity of disease, or the expected prognosis of the condition in that individual. Some markers relate to just one of these elements; others may relate to two, or occasionally all three ...
Michael Doherty, Peter C. Lanyon
openaire +3 more sources
Investigative Clinical Pharmacology
Clinical Pharmacology & Therapeutics, 2011Clinical pharmacology is an essential discipline in the development of new medicines, but the closely specified requirements of pharmaceutical industry protocols and regulatory reviewers have limited the opportunities for curiosity-driven research. Realization is growing that there is so much that is not known about the mechanisms underlying human ...
openaire +2 more sources
Microarrays and Clinical Investigations
New England Journal of Medicine, 2004Two articles in this issue of the Journal tell a similar story: primary acute myeloid leukemia (AML) may be divided into subclasses according to gene-expression profiles.
Edison T, Liu, Krishna R, Karuturi
openaire +2 more sources
HOW MUCH CLINICAL INVESTIGATION ?
The Lancet, 1972Abstract The costs of investigatory services are one of the fastest rising items in the N.H.S. bill and may soon overtake medical salaries. It may be possible to derive norms of use, designed to contain expenditure, from actual practice in hospital. A pilot inquiry into radiology and pathology requests in eight acute hospitals, involving the pattern ...
J S, Ashley, P, Pasker, J C, Beresford
openaire +2 more sources
Introduction to Clinical Investigation
JAMA, 1964THE INITIAL clinical trial is a crucial matter in the development of a new drug. The risk inherent in its first use in man, and the need to obtain a true evaluation of its action before large sums of money are invested in materials, make it imperative that the initial trial be a well-controlled study.
openaire +2 more sources
Serendipity in Clinical Investigation
JAMA: The Journal of the American Medical Association, 1969Serendipity is one of my favorite words. Not only is it euphonious but its meaning carries overtones and innuendos of precise yet ephemeral nature, as so many French words do, and so few do in our own language. The word was invented by Horace Walpole; but, with its wide popularity, the original meaning has often been corrupted to signify everything ...
openaire +2 more sources
Clinical Investigative Neuro-oncology
Archives of Internal Medicine, 1986The major thrust of the investigative work going on in the neurosurgical laboratories at Duke University, Durham, NC, in the late 1950s centered about mechanisms of regional perfusion or infusion of chemical agents into the carotid circulation. The rationale was that such technical advances might permit a more concentrated entry of antineoplastic ...
openaire +2 more sources