Results 161 to 170 of about 3,073,351 (268)

Development of an integrated clinical-laboratory scoring system for accurate HIT diagnosis. [PDF]

Blood Adv
Uzun G, Origel Romero S, Zlamal J, Jacoby J, Borst O, Rosenberger P, Poli S, Hammer S, Bakchoul T, Althaus K.   +9 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Clinical, laboratory, and medication-related factors associated with in-hospital mortality among oncology patients at a tertiary hospital in Saudi Arabia. [PDF]

Front Pharmacol
Alafnan A, Alorainan MM, Alanazi SM, Algharbi SF, Alshammari FR, Alghaslan A, Saleem H, Alghamdi S, Shaikh MF, Anwar S.   +9 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Performance of Cloud-Hosted Large Vision-Language Models on the Japanese National Examination for Clinical Laboratory Technicians: Comparative Benchmarking Study. [PDF]

JMIR Med Educ
Murakami K, Matsuzawa R, Tahara-Arai Y, Ozaki H.   +3 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Based on Raman spectroscopy and clinical laboratory tests: Developing a fusion model to predict neoadjuvant therapy response in breast cancer. [PDF]

Transl Oncol
Chen X, Li Z, Li Y, Chen Z, Song J, Wu H, Liu S, Li L, Li J.   +8 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Predictive accuracy of clinical, laboratory, and radiological scores for severe acute pancreatitis. [PDF]

Sci Rep
Abu-Elfatth A, Osman AM, Mekky MA, Mohamed SM, Ahmed M, Eltokhy SA.   +5 more
europepmc   +1 more source