microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan +4 more
wiley +1 more source
From Bits to Bedside: From Data to Knowledge in Vascular Surgery. [PDF]
Hatzl J +7 more
europepmc +1 more source
Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu +4 more
wiley +1 more source
Analysis of Quality Normative Requirements: Contributions to the Alignment and Standardization of Standards Applied in Health Laboratories. [PDF]
Fernandez SLC +5 more
europepmc +1 more source
Copine‐4 Paraneoplastic Autoimmune Encephalitis
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang +12 more
wiley +1 more source
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns +2 more
wiley +1 more source
AI readiness for molecular precision medicine supply chains: evidence from Saudi Arabia. [PDF]
El-Nakib I, Soliman K.
europepmc +1 more source
Surveillance-Driven Machine Learning for Prediction of Antimicrobial Susceptibility: An Explainable Modeling Framework using the Pfizer ATLAS Dataset (2004 - 2023). [PDF]
Mutua R +5 more
europepmc +1 more source
What do laboratories know about the pneumatic tube delivery systems they depend on? [PDF]
Jayanetti A, Badrick T.
europepmc +1 more source
Medical AI Agents for Clinical Decision Support: Viewpoint Using the Planning, Action, Reflection, and Memory (PARM) Analytical Lens. [PDF]
Dinc R, Ardic N.
europepmc +1 more source

