Results 31 to 40 of about 30,309,938 (297)

The history of pathology informatics: A global perspective

Journal of Pathology Informatics, 2013
Pathology informatics has evolved to varying levels around the world. The history of pathology informatics in different countries is a tale with many dimensions.
Seung Park, Anil V Parwani, Raymond D Aller, Lech Banach, Michael J Becich, Stephan Borkenfeld, Alexis B Carter, Bruce A Friedman, Marcial Garcia Rojo, Andrew Georgiou, Gian Kayser, Klaus Kayser, Michael Legg, Christopher Naugler, Takashi Sawai, Hal Weiner, Dennis Winsten, Liron Pantanowitz   +17 more
doaj   +1 more source

Statistical learning and big data applications

Journal of Laboratory Medicine, 2023
The amount of data generated in the field of laboratory medicine has grown to an extent that conventional laboratory information systems (LISs) are struggling to manage and analyze this complex, entangled information (“Big Data”). Statistical learning, a
Witte Harald, Blatter Tobias U., Nagabhushana Priyanka, Schär David, Ackermann James, Cadamuro Janne, Leichtle Alexander B.   +6 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Implementation of a Laboratory-Integrated Clinical Decision Support System for CKD Screening and Progression Detection in Primary Care

Biomedicines
Background: CKD remains substantially underdiagnosed and inadequately monitored. Objectives: To evaluate whether a laboratory-integrated CDSS enables opportunistic CKD detection and longitudinal surveillance in Primary Care via automated KDIGO ...
Jordi Tortosa-Carreres, Jonnathan Acevedo-Galvis, Mónica Piqueras, William Harold, Carmen Ramos, Jose Luis Górriz, Enrique Rodríguez-Borja, Francisco Brotons-Muntó, Eugenia Avelino-Hidalgo, Pablo Molina, Begoña Laíz-Marro   +10 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Mental State Assessment and Validation Using Personalized Physiological Biometrics

Frontiers in Human Neuroscience, 2018
Mental state monitoring is a critical component of current and future human-machine interfaces, including semi-autonomous driving and flying, air traffic control, decision aids, training systems, and will soon be integrated into ubiquitous products like ...
Aashish N. Patel, Michael D. Howard, Shane M. Roach, Aaron P. Jones, Natalie B. Bryant, Charles S. H. Robinson, Vincent P. Clark, Praveen K. Pilly   +7 more
doaj   +1 more source

Data mining of pediatric reference intervals

Journal of Laboratory Medicine, 2021
Laboratory tests are essential to assess the health status and to guide patient care in individuals of all ages. The interpretation of quantitative test results requires availability of appropriate reference intervals, and reference intervals in children
Zierk Jakob, Metzler Markus, Rauh Manfred   +2 more
doaj   +1 more source

Speaking of sepsis: semantics, syntax, and slang

Frontiers in Medicine, 2023
Medical language is in a constant state of evolution. Its grammar and vocabulary are not fixed by rigid rules. The interdisciplinary field of sepsis has become a meeting point for new insights arising from advances in systems biology, epidemiology ...
Tim J. J. Inglis, Tim J. J. Inglis, Tim J. J. Inglis   +2 more
doaj   +1 more source

Implementation of AI systems in the clinical laboratory: insights from an expert survey and recommendations for best practice

Clinical Chemistry and Laboratory Medicine
Objectives Despite growing interest in artificial intelligence (AI) and machine learning (ML), many laboratory professionals lack experience with developing in-house AI systems or implementing those supplied by external providers.
He S. Yang, H. Çubukçu, F. Del Ben, Xincen Duan, Jennifer Feng, G. Frans, D. Gruson, Michael King, Javier Nieto-Moragas, Bei-Li Wang, Fei Wang   +10 more
semanticscholar   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source