Results 71 to 80 of about 1,619,987 (346)

Southern African Treatment Resistance Network (SATuRN) RegaDB HIV drug resistance and clinical management database: supporting patient management, surveillance and research in southern Africa [PDF]

, 2014
Substantial amounts of data have been generated from patient management and academic exercises designed to better understand the human immunodeficiency virus (HIV) epidemic and design interventions to control it.
Bester, Armand, Chetty, Terusha, Danaviah, Siva, De Oliveira, Tulio, Goedhals, Dominique, Iwuji, Collins, Lessells, Richard, Manasa, Justen, McGrath, Nuala, Moodley, Pravi, Naidu, Kevindra, Rossouw, Theresa, Seebregts, Christopher J, Singh, Lavanya, Skingsley, Andrew, Stott, Katharine, Van Vuuren, Cloete, Van Zyl, Gert   +17 more
core   +3 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Use of artificial intelligence in analytical systems for the clinical laboratory

Journal of Automatic Chemistry, 1995
The incorporation of information-processing technology into analytical systems in the form of standard computing software has recently been advanced by the introduction of artificial intelligence (AI), both as expert systems and as neural networks.
J. Place, A. Truchaud, K. Ozawa, H. Pardue, P. Schnipelsky   +4 more
semanticscholar   +1 more source

Clinical guidelines as plans: An ontological theory [PDF]

, 2006
Clinical guidelines are special types of plans realized by collective agents. We provide an ontological theory of such plans that is designed to support the construction of a framework in which guideline-based information systems can be employed in the ...
Gangemi, Aldo, Kumar, Anand, Pisanelli, Domenica, Smith, Barry, Stefanelli, Mario   +4 more
core   +1 more source

The development of non-coding RNA ontology [PDF]

, 2016
Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data ...
Blake, Judith, de Silva, Nisansa, Dou, Deijing, Eilbeck, Karen, Huan, Jun, Huang, Jingshan, Huang, Weili, Jiang, Guoqian, Kasukurthi, Mohan Vamsi, Lin, Yu, Natale, Darren, Ruttenberg, Alan, Smith, Barry, Strachan, Harrison, Wu, Bin, Zimmermann, Michael   +15 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Focal Spot, Winter 2006/2007 [PDF]

, 2007
https://digitalcommons.wustl.edu/focal_spot_archives/1104/thumbnail ...

core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

E-infrastructures fostering multi-centre collaborative research into the intensive care management of patients with brain injury [PDF]

, 2009
Clinical research is becoming ever more collaborative with multi-centre trials now a common practice. With this in mind, never has it been more important to have secure access to data and, in so doing, tackle the challenges of inter-organisational data ...
Piper, I., Sinnott, R.O.
core  

Invasive meningococcal disease in the Veneto region of Italy: A capture-recapture analysis for assessing the effectiveness of an integrated surveillance system [PDF]

, 2017
open8noBACKGROUND: Epidemiology of Neisseria meningitidis has been changing since the introduction of universal vaccination programmes against meningococcal serogroup C (MenC) and meningococcal serogroup B (MenB) has now become dominant.
Baldo, Vincenzo, Baldovin, Tatjana, Bertoncello, Chiara, Cocchio, Silvia, Furlan, Patrizia, Lazzari, Roberta, Russo, Francesca, Saia, Mario   +7 more
core   +1 more source