Results 151 to 160 of about 878,073 (326)
040 The C3H/HeJ mouse model of alopecia areata as a resource for training graduate and undergraduate students in clinical laboratory research techniques [PDF]
C.S. Potter
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We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei+6 more
wiley +1 more source
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel+13 more
wiley +1 more source
Urine culture and partial urinalysis in the diagnosis of urinary tract infections
Background: urinary tract infections are one of the most frequent causes of infectious disease in the medical practice.Objective: to describe the results of the sample processing of urine culture and partial urinalysis for the diagnosis of urinary tract ...
MIlagros de la Caridad Milá-Pascual+2 more
doaj
The Use of Ultramicro Techniques in the Clinical Laboratory No. 1 Apparatus and Manufacture of Pipettes [PDF]
T. W. MacFarlane
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We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang+9 more
wiley +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal+8 more
wiley +1 more source
Electron FLASH platform for pre-clinical research: LINAC modification, simplification of pulse control and dosimetry [PDF]
Background: FLASH radiotherapy is a treatment regime that delivers therapeutic dose to tumors at an ultra-high dose rate while maintaining adequate normal tissue sparing. However, a comprehensive understanding of the underlying mechanisms, potential late toxicities, and optimal fractionation schemes is important for successful clinical translation ...
arxiv
A review of techniques and results obtained in one laboratory by an integrated system of methods designed for routine clinical flow cytometric DNA analysis [PDF]
Lars L. Vindeløv, Ib Jarle Christensen
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