Results 201 to 210 of about 99,850 (296)

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

open access: yesiNew Medicine, EarlyView.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu   +10 more
wiley   +1 more source

Mimicking DOUGONG brackets orchestrate regulating inflammation and mechanical stimuli for osteochondral regeneration using 3D printing

open access: yesInterdisciplinary Medicine, EarlyView.
Akermanite scaffolds promote osteogenic differentiation of BMSCs through regulating the PI3K/Akt signaling pathway, and strontium ions enhance the akermanite effects by mediating the cytokine‐cytokine receptor interaction pathway. Thus, the enhancements of osteogenesis in subchondral bone coupled with the chondral‐promoting effects of chondrocytes ...
Bo Li   +15 more
wiley   +1 more source

Score Reliability and Validity of a Mexican Dialect Spanish Translation of the Satisfaction With Life Scale With Mexican Earthquake Survivors

open access: yesJournal of Counseling &Development, EarlyView.
ABSTRACT Satisfaction with life is a complex construct, with many implications for overall well‐being. This study explored the psychometric characteristics of the Satisfaction with Life Scale (SWLS) scores on Mexican dialect Spanish‐speaking participants who endured the 2017 Mexican earthquake.
Geneghee Kim   +3 more
wiley   +1 more source

Do Artificial Intelligence Clients Speak Like Human Clients? Exploring GPT‐4's Content‐Level Performance in Counseling Role‐Play

open access: yesJournal of Counseling &Development, EarlyView.
ABSTRACT Traditional role‐playing methods in counselor education, such as peer counseling and actor‐based simulations, enhance trainee competencies but have also created ethical dilemmas. These methods are not cost effective and may not capture and address client diversity.
Xihe Tian   +5 more
wiley   +1 more source

A Novel Frameshift Variant c.1023_1029del (p.Asp342ArgfsTer54) Leading to Extended Incorrect Protein C Termini in HOMER2 Causing Autosomal Dominant Nonsyndromic Hearing Loss

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
We identified a novel c.1023_1029del (p.Asp342ArgfsTer54) frameshift variant in the HOMER2 gene that causes ADNSHL in a Chinese family with progressive, post‐lingual sensorineural hearing loss. The c.1023_1029del variant deletes 7 nucleotides, leading to an extended incorrect protein C terminus and marks the sixth pathogenic (or likely pathogenic ...
Li‐Ting Peng   +9 more
wiley   +1 more source

Manual Dexterity Abilities and Dual Tasking in Children With Developmental Coordination Disorder and Typically Developing Children

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Poor manual skills in children with Developmental Coordination Disorder (DCD) may be dependent on task complexity and due to difficulties in the automatization phase of the motor learning process. Increased task demands and the dual‐task paradigm can be used to test these hypotheses.
Eleonora Bieber   +8 more
wiley   +1 more source

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