Results 41 to 50 of about 1,157,477 (291)

Autoimmune diseases and their manifestations on oral cavity: diagnosis and clinical management [PDF]

, 2018
Oral signs are frequently the first manifestation of autoimmune diseases. For this reason, dentists play an important role in the detection of emerging autoimmune pathologies.
Bossù, Maurizio, Di Carlo, Gabriele, Giovarruscio, Francesca, Polimeni, Antonella, Saccucci, Matteo, Salucci, Alessandro   +5 more
core   +2 more sources

The role of gender, age and localization in the clinical manifestation of the cerebral bifurcational-hemodynamic arterial aneurysms

Ендоваскулярна нейрорентгенохірургія, 2020
Objective ‒ to evaluate the influence of age, gender and localization on the clinical manifestation of cerebral bifurcational-hemodynamic arterial aneurysms (AA). Materials and methods.
S.O. Lytvak, M.V. Eleinik, L.M. Yakovenko, T.A. Malysheva   +3 more
doaj   +1 more source

DIAGNOSIS OF EARLY PSORIATIC ARTHRITIS – CLINICAL CHALLENGES

Arta Medica, 2023
Objectives. The aim was to study clinical manifestations in psoriatic arthritis: enthesities, dactylitis, peripheral and axial arthritis, skin expressions, for early diagnosis, which would allow the establishment of an adjusted treatment and developing ...
Eugeniu Russu
doaj   +1 more source

Orbitofrontal epilepsy: Electroclinical analysis of surgical cases and literature review [PDF]

, 2004
Clinical and electrographic data were reviewed on 2 of our patients with orbitofrontal epilepsy who were seizure free at 5-year follow-up, and on 2 similar patients from the literature.
King, Don W., Loring, David W., Sillay, Karl, Smith, Joseph R., Winkler, Peter   +4 more
core   +1 more source

Xerosis: from pathogenesis to solving practical problems [PDF]

Vestnik Dermatologii i Venerologii
Xerosis is a widespread symptom of dermatoses of various etiologies and pathogenetic mechanisms, which is recorded in people of different ages with a wide range of frequency and severity.
Irina E. Torshina
doaj   +1 more source

Tumors in von Hippel–Lindau Syndrome: From Head to Toe—Comprehensive State-of-the-Art Review [PDF]

, 2018
Von Hippel–Lindau syndrome (VHL) is an autosomal-dominant hereditary tumor disease that arises owing to germline mutations in the VHL gene, located on the short arm of chromosome 3.
Bhalla, Sanjeev, Ganeshan, Dhakshinamoorthy, Lubner, Meghan G., Menias, Christine O., Pickhardt, Perry J., Ramalingam, Preetha, Sandrasegaran, Kumaresan   +6 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Posterior reversible encephalopathy syndrome (PRES) after bevacizumab therapy for metastatic colorectal cancer. [PDF]

, 2018
Posterior reversible encephalopathy syndrome (PRES) is an increasingly recognizable neuro-clinical syndrome. Clinical and neurological manifestations of PRES include hypertension, headache, encephalopathy, seizures, and symmetrical white matter changes ...
Ghani, Ali, Hamid, Mohsin, Lashari, MD, Bilal, Malik, Faizan, Micaily, Ida, Sarwar, MD, Usman   +5 more
core   +2 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source