Results 241 to 250 of about 3,580,948 (312)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Awareness, Experiences, and Attitudes Toward Preprints Among Medical Academics: Convergent Mixed Methods Study. [PDF]

JMIRx Med
Sevim M, Karamese B, Alparslan Z.
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Study protocol: A randomized controlled trial of chemoradiotherapy versus chemotherapy as neoadjuvant therapy for resectable pancreatic cancer (CSGO-HBP-027). [PDF]

PLoS One
Tomimaru Y, Akita H, Tamari K, Maeda S, Wada H, Iwagami Y, Koga C, Hama N, Tomokuni A, Kobayashi S, Asaoka T, Tsujie M, Tanemura M, Murakami M, Katsura Y, Shimizu J, Yamashita M, Sakamoto S, Okamura S, Yamada T, Doki Y, Eguchi H.   +21 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Autoimmune myelofibrosis with a <i>TLR8</i> gain-of-function defect. [PDF]

Leuk Res Rep
Qu S, Zhang P, Xu Z, Qin T, Li B, Xiao Z.   +5 more
europepmc   +1 more source

Correction: Widespread 3'UTR capped RNAs derive from G-rich regions in proximity to AGO2 binding sites. [PDF]

BMC Biol
Haberman N, Digby H, Faraway R, Cheung R, Chakrabarti AM, Jobbins AM, Parr C, Yasuzawa K, Kasukawa T, Yip CW, Kato M, Takahashi H, Carninci P, Vernia S, Ule J, Sibley CR, Martinez-Sanchez A, Lenhard B.   +17 more
europepmc   +1 more source

Surgical Challenges in Papillary Thyroid Cancer Patient With Kartagener's Syndrome: A Case Report. [PDF]

Clin Case Rep
Huang J, Zhao T, Wei M.
europepmc   +1 more source

A Machine Learning-Based Model for Individualized Prediction of Vancomycin Concentration-Time Curves in ICU Patients. [PDF]

Pharmacol Res Perspect
Wang JY, Hu J, Chen Y, Li S, Peng JM, Dong R, Hu XY, Jiang W, Wang CY, Weng L, Du B, China Critical Care Clinical Trials Group (CCCCTG).   +11 more
europepmc   +1 more source

Concurrent hepatic cirrhosis and chronic lymphocytic leukemia: a challenging coexistence: a case report. [PDF]

J Med Case Rep
Mahani FK, Nezhad NZ, Ghaderi R, Jafari E, Khazaeli M, Kermanshahaninejad SO, Shamsinejad B.   +6 more
europepmc   +1 more source