Results 161 to 170 of about 16,573,156 (294)

A study on the Dilemmas faced by Chinese clinical medicine interns preparing for postgraduate entrance examinations: a grounded theory approach. [PDF]

Med Educ Online
Xu H, Zhu H, Du J, Wang X, Chen H, Jiang S, Luo B, Sun W, Ke Q, Chen L.   +9 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Rastreamento de resultados adversos nas internações do Sistema Único de Saúde

Revista de Saúde Pública
OBJETIVO: Descrever a frequência de rastreadores de potenciais resultados adversos em internações no Sistema Único de Saúde. MÉTODOS: Estudo retrospectivo, incluindo as internações de adultos na clínica médica (n = 3.565.811) e clínica cirúrgica (n = 2 ...
Monica Aguilar Estevam Dias, Monica Martins, Nair Navarro   +2 more
doaj  

Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline

Journal of Clinical Sleep Medicine (JCSM), 2017
V. Kapur, D. Auckley, S. Chowdhuri, David C Kuhlmann, R. Mehra, K. Ramar, C. Harrod   +6 more
semanticscholar   +1 more source

Machine Learning and Artificial Intelligence in Clinical Medicine-Trends, Impact, and Future Directions. [PDF]

J Clin Med
Andrès E, Escobar C, Doi K.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Cognitive Bias in Clinical Medicine

The Journal of the Royal College of Physicians of Edinburgh, 2018
E. O’Sullivan, S. Schofield
semanticscholar   +1 more source

A bibliometric analysis of the global research landscape on artificial intelligence applications in clinical medicine (2010-2025). [PDF]

Digit Health
Li M, Chen S, Liu S, Yang J, Qin Y, Chen Y, Tai X.   +6 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Microvesicles, exosomes and their combinations with cytoplasmic organelles: from their discovery to their innovative roles in clinical medicine. [PDF]

Biol Direct
Meldolesi J.
europepmc   +1 more source