Results 201 to 210 of about 4,829,298 (254)

Editorial: Targeting the interleukin-1β/interleukin-6/C-reactive protein pathway in clinical medicine - a road map to clinical trial design. [PDF]

Front Cardiovasc Med
Torzewski J, Sheriff A, Filep JG, Peter K, Ridker PM.   +4 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Physician's role(s): Conceptual redesign and implementation of the lecture series "Introduction to clinical medicine" for the promotion of professional identity formation based on the physician's roles of the CanMEDS framework. [PDF]

GMS J Med Educ
Schumm M, Apondo S, Schneider A, Berberat PO.   +3 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Effectiveness of flipped classrooms in Chinese students of clinical medicine major undergoing clinical practice: a meta-analysis. [PDF]

BMC Med Educ
Sun X, Yuan X, Zhang L, Zhang Y, Xiao X, Liu H, Ma F.   +6 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Assessing clinical medicine students' acceptance of large language model: based on technology acceptance model. [PDF]

BMC Med Educ
Liu F, Chang X, Zhu Q, Huang Y, Li Y, Wang H.   +5 more
europepmc   +1 more source

A survey of attitudes towards the curriculum for clinical medicine postgraduates pursuing professional master's degrees: perspectives of supervisors and students. [PDF]

Front Med (Lausanne)
Xu R, Wu J, Jin X, Tang M, Pang C, Yang Z, Yu H.   +6 more
europepmc   +1 more source

Performance of ChatGPT on Chinese Master's Degree Entrance Examination in Clinical Medicine. [PDF]

PLoS One
Li KC, Bu ZJ, Shahjalal M, He BX, Zhuang ZF, Li C, Liu JP, Wang B, Liu ZL.   +8 more
europepmc   +1 more source